PI-3065

目录号: A14338

p110δ 抑制剂

PI-3065

PI-3065 Chemical Structure

CAS NO. 955977-50-1

PI-3065是p110δ激酶的小分子和选择性抑制剂,Ki值为1.5nM,IC50值为5nM。

库存: 现货

规格 价格 数量
5 mg
¥ 630.00
10 mg
¥ 1,050.00
25 mg
¥ 2,100.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

PI-3065是p110δ激酶的小分子和选择性抑制剂,Ki值为1.5nM,IC50值为5nM。
Targets
Target Value
p110δIC50: 15nM
p110βIC50: 1078nM
p110αIC50: 2299nM
mTORIC50: 9082nM
DNA-PKIC50: >10000nM
p110γIC50: 27542nM
In vitro DMSO Warmed: 50 mg/mL (98.68 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.74 mL 98.69 mL 197.38 mL
0.5 mM 3.95 mL 19.74 mL 39.48 mL
1 mM 1.97 mL 9.87 mL 19.74 mL
5 mM 0.39 mL 1.97 mL 3.95 mL

*The above data is based on the productmolecular weight 506.64. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A14338
作用机制 Inhibitor (抑制剂)
M. Wt 506.64
Formula C27H31FN6OS
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 955977-50-1
Synonyms PI3065, PI 3065
SMILES C1CC1CN2CCN(CC2)CC3=CC4=C(S3)C(=NC(=N4)C5=C(C=CC6=C5C=CN6)F)N7CCOCC7

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