Pimavanserin

Name: Pimavanserin
SKU: A15884

目录号: A15884

Serotonin2A Receptor Inverse 激动剂

Pimavanserin Chemical Structure

CAS NO. 706782-28-7

Pimavanserin是一种有效的选择性5-羟色胺5-HT2A反向激动剂，pIC50为8.73，用于治疗与帕金森氏病有关的精神病。

库存：现货

规格	价格	数量
10 mg	￥ 560.00
25 mg	￥ 840.00
50 mg	￥ 1,400.00

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生物活性

Pimavanserin是一种有效的选择性5-羟色胺5-HT2A反向激动剂，pIC50为8.73，用于治疗与帕金森氏病有关的精神病。

靶点信息

5-HT2A
8.73(pIC50)

溶解度 *

In vitro	DMSO	95 mg/mL (94.51 mM)
	Water	95 mg/mL (94.51 mM)
	Ethanol	95 mg/mL (94.51 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	9.95 mL	49.74 mL	99.48 mL
0.5 mM	1.99 mL	9.95 mL	19.9 mL
1 mM	0.99 mL	4.97 mL	9.95 mL
5 mM	0.2 mL	0.99 mL	1.99 mL

*The above data is based on the productmolecular weight 1005.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A15884
作用机制	Agonist (激动剂)
M. Wt	1005.2
Formula	C50H68F2N6O4.C4H6O6
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	706782-28-7
Synonyms	Pimavanserin tartrate
SMILES	CC(C)COC1=CC=C(C=C1)CNC(=O)N(CC2=CC=C(C=C2)F)C3CCN(CC3)C.CC(C)COC1=CC=C(C=C1)CNC(=O)N(CC2=CC=C(C=C2)F)C3CCN(CC3)C.C(C(C(=O)O)O)(C(=O)O)O