Plerixafor 8HCl (DB06809)

Name: Plerixafor 8HCl (DB06809)
SKU: A10913

目录号: A10913

CXCR4 拮抗剂

Product Citations (3)

Plerixafor 8HCl (DB06809) Chemical Structure

CAS NO. 155148-31-5

Plerixafor 8HCl (DB06809)是CXCR4趋化因子受体拮抗剂，作用于CXCR4和CXCL12介导调节的趋化性， IC50分别为44 nM和5.7 nM。

库存：现货

规格	价格	数量
10 mg	￥ 420.00
25 mg	￥ 700.00
50 mg	￥ 1,120.00
100 mg	￥ 2,170.00

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生物活性

Plerixafor 8HCl (DB06809)是CXCR4趋化因子受体拮抗剂，作用于CXCR4和CXCL12介导调节的趋化性， IC50分别为44 nM和5.7 nM。

靶点信息

CXCL12-mediated chemotaxis (Cell-free assay)	CXCR4 (Cell-free assay)
5.7 nM	44 nM

溶解度 *

In vitro (25°C)	DMSO	Insoluble
	Water	91 mg/mL (114.54 mM)
	Ethanol	Insoluble
In vivo	Saline	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	12.59 mL	62.93 mL	125.87 mL
0.5 mM	2.52 mL	12.59 mL	25.17 mL
1 mM	1.26 mL	6.29 mL	12.59 mL
5 mM	0.25 mL	1.26 mL	2.52 mL

*The above data is based on the productmolecular weight 794.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A10913
作用机制	Antagonist (拮抗剂)
M. Wt	794.5
Formula	C28H54N8.8HCl
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	155148-31-5
Synonyms	DB06809, AMD3100, Mozobil
SMILES	C1CNCCNCCCN(CCNC1)CC2=CC=C(C=C2)CN3CCCNCCNCCCNCC3.Cl.Cl.Cl.Cl.Cl.Cl.Cl.Cl