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PNRI-299是一种选择性AP-1转录抑制剂，IC50为20 uM，不影响NF-κB转录（最高200μM）或硫氧还蛋白（最高200μM）。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.91 mL | 124.57 mL | 249.15 mL |
| 0.5 mM | 4.98 mL | 24.91 mL | 49.83 mL |
| 1 mM | 2.49 mL | 12.46 mL | 24.91 mL |
| 5 mM | 0.5 mL | 2.49 mL | 4.98 mL |
*The above data is based on the productmolecular weight 401.37. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A16305 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 401.37 |
| Formula | C21H15N5O4 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 550368-41-7 |
| Synonyms | PNRI299, PNRI 299 |
| SMILES | C1C(=O)C=C(N2N1C(=O)N(C2=O)C3=CC=CC(=C3)C#N)C(=O)NCC4=CC=CC=C4 |
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