Potassium Channels
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Cesium chloride
Catalog No. A15341 Potassium channel blockerCesium chloride是钾通道阻滞剂。抑制起搏器电流(If)和超极化激活的阳离子电流(Ih)。通过灭活GSK-3β来防止血清和钾缺乏的小脑颗粒神经元中caspase-3的激活和神经元凋亡。 了解更多 -
4-Aminopyridine
Catalog No. A17490 Potassium channel blockerDalfampridine is a potassium channel blocker used to help multiple sclerosis patients walk. 了解更多 -
ML418
Catalog No. A18426 Kir7.1 potassium channels blockerML418 is a selective, sub-micromolar pore blocker of Kir7.1 potassium channels. The inward rectifier potassium (Kir) channel Kir7.1 (KCNJ13) is a key regulator of melanocortin signaling in the brain, electrolyte homeostasis in the eye, and uterine muscle contractility during pregnancy. 了解更多 -
JNJ 303
Catalog No. A20952 -
TAK-438 (vonoprazan)
Catalog No. A11239 -
Orphenadrine citrate
Catalog No. A11712 -
PAP-1 (5-(4-Phenoxybutoxy)psoralen)
Catalog No. A11521 Kv1.3 blockerPAP-1 (5-(4-Phenoxybutoxy)psoralen) 是一种有效的,选择性的,口服活性的?Kv1.3?阻滞剂 (EC50=2 nM)。PAP-1 以使用依赖性方式阻止 Kv1.3,并通过优先绑定到通道的 C 型灭活状态来起作用。 了解更多 -
E-4031 dihydrochloride
Catalog No. A12857 K+ channel blocker?E-4031 dihydrochloride是KV11.1(hERG)通道的选择性阻滞剂;禁止快速延迟整流器K+电流(IKr)。 了解更多 -
Vernakalant HCl
Catalog No. A15275 Ion channel blockerVernakalant hydrochloride是一种研究性混合离子通道阻滞剂,可以以2至5 mg/kg的剂量终止人的急性心房纤颤(AF),并且与现有药物相比,对房颤的选择性更高。在抗心律不齐的治疗中。 了解更多