Potassium Channels

11 个项目

每页

设置升序顺序
  1. Cesium chloride

    Catalog No. A15341
    Quick View
    Potassium channel blocker
    Cesium chloride是钾通道阻滞剂。抑制起搏器电流(If)和超极化激活的阳离子电流(Ih)。通过灭活GSK-3β来防止血清和钾缺乏的小脑颗粒神经元中caspase-3的激活和神经元凋亡。 了解更多
  2. 4-Aminopyridine

    Catalog No. A17490
    Quick View
    Potassium channel blocker
    Dalfampridine is a potassium channel blocker used to help multiple sclerosis patients walk. 了解更多
  3. ML418

    Catalog No. A18426
    Quick View
    Kir7.1 potassium channels blocker
    ML418 is a selective, sub-micromolar pore blocker of Kir7.1 potassium channels. The inward rectifier potassium (Kir) channel Kir7.1 (KCNJ13) is a key regulator of melanocortin signaling in the brain, electrolyte homeostasis in the eye, and uterine muscle contractility during pregnancy. 了解更多
  4. JNJ 303

    Catalog No. A20952
    Quick View
    IKs blocker
    JNJ 303 is a potent IKs blocker with an IC50 value of 64 nM. 了解更多
  5. TAK-438 (vonoprazan)

    Catalog No. A11239
    Quick View
    potassium-competitive acid Blocker
    TAK-438 (vonoprazan)是一种新型的钾竞争酸阻滞剂。 了解更多
  6. Orphenadrine citrate

    Catalog No. A11712
    Quick View
    NMDA receptor 拮抗剂
    Orphenadrine柠檬酸盐是NMDA受体拮抗剂,Ki为6.0μM,还是HERG钾离子通道阻断剂。 了解更多
  7. PAP-1 (5-(4-Phenoxybutoxy)psoralen)

    Catalog No. A11521
    Quick View
    Kv1.3 blocker
    PAP-1 (5-(4-Phenoxybutoxy)psoralen) 是一种有效的,选择性的,口服活性的?Kv1.3?阻滞剂 (EC50=2 nM)。PAP-1 以使用依赖性方式阻止 Kv1.3,并通过优先绑定到通道的 C 型灭活状态来起作用。 了解更多
  8. TRAM-34

    Catalog No. A12783
    Quick View
    Potassium Channel Blocker
    TRAM-34是中等电导Ca2+激活的K+通道(KCa3.1)(Kd = 20 nM)的高度选择性阻滞剂。在KV,BKCa,KCa2,Na+,CRAC和Cl-通道上具有200-1500倍的选择性。抑制有丝分裂刺激对淋巴细胞的激活。 了解更多
  9. E-4031 dihydrochloride

    Catalog No. A12857
    Quick View
    K+ channel blocker?
    E-4031 dihydrochloride是KV11.1(hERG)通道的选择性阻滞剂;禁止快速延迟整流器K+电流(IKr)。 了解更多
  10. Glyburide

    Catalog No. A10433
    Quick View
    K+ channel and CFTR Cl- channel blocker
    Glyburide (Glibenclamide) 是一种抗糖尿病化合物,是一类磺脲类药物。 了解更多
  11. Vernakalant HCl

    Catalog No. A15275
    Quick View
    Ion channel blocker
    Vernakalant hydrochloride是一种研究性混合离子通道阻滞剂,可以以2至5 mg/kg的剂量终止人的急性心房纤颤(AF),并且与现有药物相比,对房颤的选择性更高。在抗心律不齐的治疗中。 了解更多

11 个项目

每页

设置升序顺序
Rewards