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PPQ-102是一种化合物,其靶向cftr的胞内核苷酸结合结构域,并以电压依赖性和可逆的方式抑制cftr介导的氯离子电流。
In vitro | DMSO | 48 mg/mL (109.47 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 22.81 mL | 114.03 mL | 228.06 mL |
0.5 mM | 4.56 mL | 22.81 mL | 45.61 mL |
1 mM | 2.28 mL | 11.4 mL | 22.81 mL |
5 mM | 0.46 mL | 2.28 mL | 4.56 mL |
*The above data is based on the productmolecular weight 438.48. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A13000 |
---|---|
作用机制 | Inhibitor (抑制剂) |
M. Wt | 438.48 |
Formula | C26H22N4O3 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 931706-15-9 |
Synonyms | PPQ102, PPQ 102 |
SMILES | CC1=CC=C(O1)C2C3=C4C(=C(N3C5=CC=CC=C5N2)C6=CC=CC=C6)C(=O)N(C(=O)N4C)C |
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