Pravastatin sodium

Name: Pravastatin sodium
SKU: A11912

目录号: A11912

HMG-CoA reductase 抑制剂

Pravastatin sodium Chemical Structure

CAS NO. 81131-70-6

Pravastatin sodium是3-羟基-3-甲基辅酶A（HMG-CoA）还原酶的水溶性竞争性抑制剂。有效阻断体内胆固醇合成（Ki?1 nM）并显示出心脏保护特性。

库存：现货

规格	价格	数量
25 mg	￥ 280.00
50 mg	￥ 420.00
100 mg	￥ 700.00
250 mg	￥ 1,260.00
10mM * 1mL in DMSO	￥ 462.00

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产品详情

生物活性

Pravastatin sodium是3-羟基-3-甲基辅酶A（HMG-CoA）还原酶的水溶性竞争性抑制剂。有效阻断体内胆固醇合成（Ki?1 nM）并显示出心脏保护特性。

靶点信息

HMG-CoA reductase
5.6 μM

溶解度 *

In vitro	DMSO	79 mg/mL (176.92 mM)
	Water	79 mg/mL (176.92 mM)
	Ethanol	11 mg/mL (24.63 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.4 mL	111.98 mL	223.96 mL
0.5 mM	4.48 mL	22.4 mL	44.79 mL
1 mM	2.24 mL	11.2 mL	22.4 mL
5 mM	0.45 mL	2.24 mL	4.48 mL

*The above data is based on the productmolecular weight 446.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A11912
作用机制	Inhibitor (抑制剂)
M. Wt	446.51
Formula	C23H35NaO7
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	81131-70-6
Synonyms	Eptastatin sodium
SMILES	CC[C@H](C)C(=O)O[C@H]1C[C@@H](C=C2[C@H]1[C@H]([C@H](C=C2)C)CC[C@H](C[C@H](CC(=O)[O-])O)O)O.[Na+]