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Cryptotanshinone

Catalog No. A10244
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Stat3 抑制剂

Cryptotanshinone是一种STAT3抑制剂，在DU145细胞中能显着阻断STAT3 Tyr705磷酸化，但不能阻断STAT3 Ser727磷酸化，并显着抑制JAK2磷酸化，IC50为?5μM，而不影响上游激酶c的磷酸化。了解更多

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CYC116 (CYC-116)

Catalog No. A10248
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Aurora Kinase 抑制剂

CYC116 (CYC-116)是一种有效的Aurora A/B抑制剂，Ki为8.0 nM/9.2 nM，对VEGFR2(Ki为44 nM)作用稍弱。了解更多

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Cytisine (Baphitoxine, Sophorine)

Catalog No. A10266
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Cytisine (Baphitoxine,Sophorine)是一种烟碱型乙酰胆碱受体激动剂。了解更多

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Dexamethasone

Catalog No. A10299
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Dexamethasone是一类固醇药物的糖皮质激素类的有效合成成员。它起着抗炎和免疫抑制剂的作用。它的功效约为天然激素氢化可的松的20-30倍，是泼尼松的4-5倍。了解更多

Product Citations (2)

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- Ken Kobayashi, .et al. Lactose on the basolateral side of mammary epithelial cells inhibits milk production concomitantly with signal transducer and activator of transcription 5 inactivation, Cell Tissue Res, 2022, Sep;389(3):501-515 PMID: 35748981
- Reiko Watanabe, .et al. Development of an In Silico Prediction Model for P-glycoprotein Efflux Potential in Brain Capillary Endothelial Cells toward the Prediction of Brain Penetration, J Med Chem, 2021, Mar 11;64(5):2725-2738 PMID: 33619967
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Dihydroartemisinin

Catalog No. A10310
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Dihydroartemisinin是所有青蒿素化合物（青蒿素，青蒿琥酯，青蒿素等）的活性代谢产物，本身也可以用作药物。它是青蒿素的半合成衍生物，被广泛用作制备其他由青蒿素衍生的抗疟药物的中间体。了解更多

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- Xinyu Zhou, .et al. Artemisinin Derivatives Stimulate DR5-Specific TRAIL-Induced Apoptosis by Regulating Wildtype P53, Cancers (Basel), 2020, Sep; 12(9): 2514 PMID: 32899699
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Dioscin (Collettiside III)

Catalog No. A10314
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Dioscin是皂苷提取的，Polygonatum Zanlanscianense Pamp分离的，IC50为2.6、0.8、7.5和4.5μM，分别用于抑制MDA-MB-435，H14，HL60和HeLa细胞系的生长。了解更多

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Diosmetin

Catalog No. A10316
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Diosmetin是在Spearmint，Oregano，和许多其他植物中发现的生物类黄酮。了解更多

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- Shin-ichi Adachi, .et al. Comparative effects of quercetin, luteolin, apigenin and their related polyphenols on uric acid production in cultured hepatocytes and suppression of purine bodies-induced hyperuricemia by rutin in mice, Cytotechnology, 2021, February 02
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DMXAA (ASA404, Vadimezan)

Catalog No. A10324
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Vascular Disrupting Agent (VDA)

DMXAA (ASA404,Vadimezan)是一种肿瘤血管破坏剂（tumor-VDA），也是一种DT-diaphorase的竞争性抑制剂。了解更多

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- Zhang X, .et al. Discovery and Mechanistic Study of a Novel Human-Stimulator-of-Interferon-Genes Agonist, ACS Infect Dis, 2019, May 14 PMID: 31060350
- Bowei Liu, .et al. A cell-based high throughput screening assay for the discovery of cGAS-STING pathway agonists, Antiviral Res, 2017, Nov; 147: 37-46 PMID: 28982551
- Fang Guo, .et al. Activation of Stimulator of Interferon Genes in Hepatocytes Suppresses the Replication of Hepatitis B Virus, Antimicrob Agents Chemother, 2017, Oct; 61(10): e00771-17 PMID: 28717041
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Doripenem Hydrate

Catalog No. A10332
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Doripenem Hydrate是一种超广谱的，注射用的抗生素。了解更多

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- Maria Yuliana, .et al. Low-cost structured alginate-immobilized bentonite beads designed for an effective removal of persistent antibiotics from aqueous solution, Environ Res, 2021, Oct 2;112162 PMID: 34610325
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Dutasteride (Avodart)

Catalog No. A10338
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dual 5alpha-reductase 抑制剂

Dutasteride (Avodart)是双重的5-a还原酶抑制剂，可抑制睾丸激素转化为二氢睾丸激素（DHT）。了解更多

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- Makoto Ishikawa, .et al. Additive neuroprotective effects of 24(S)-hydroxycholesterol and allopregnanolone in an ex vivo rat glaucoma model, Sci Rep, 2018, 8: 12851 PMID: 30150786
- Makoto Ishikawa, .et al. TSPO activation modulates the effects of high pressure in a rat ex vivo glaucoma model, Neuropharmacology, 2016, Dec; 111: 142-159 PMID: 27596950
- Makoto Ishikawa, .et al. Neurosteroids Are Endogenous Neuroprotectants in an Ex Vivo Glaucoma Model, Invest Ophthalmol Vis Sci., 2014, 55(12): 8531-8541 PMID: 25406290
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E7080 (Lenvatinib)

Catalog No. A10340
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VEGFR 抑制剂

E7080 (Lenvatinib)是一种多激酶抑制剂，可同时抑制VEGFR2和VEGFR3激酶。了解更多

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- Mai Nakahara, .et al. Effect of Lenvatinib treatment on the cell cycle and microRNA profile in hepatocellular carcinoma cells, Biomed Rep, 2022, Aug 3;17(4):78 PMID: 36158319
- Paula Sagmeister, .et al. Comparative Response of HCC Cells to TKIs: Modified in vitro Testing and Descriptive Expression Analysis, J Hepatocell Carcinoma, 2022, Jul 9;9:595-607 PMID: 35845819
- Aya Hasan Alshammari, .et al. Discrimination of hand-foot skin reaction caused by tyrosine kinase inhibitors based on direct keratinocyte toxicity and vascular endothelial growth factor receptor-2 inhibition, Biochem Pharmacol, 2022, Mar;197:114914 PMID: 35041812
- Keisuke Enomoto, .et al. Synergistic Effects of Lenvatinib (E7080) and MEK Inhibitors against Anaplastic Thyroid Cancer in Preclinical Models, Cancers (Basel), 2021, Feb 18;13(4):862 PMID: 33670725
- Jindal A, .et al. Milciclib and sorafenib synergistically downregulate c-Myc to suppress tumor growth in an orthotopic murine model of human hepatocellular carcinoma, J Transl Sci, 2020, 7: 1-10
- Koide H, .et al. Substrate-dependent effects of molecular-targeted anticancer agents on activity of organic anion transporting polypeptide 1B1, Xenobiotica, 2018, Oct;48(10):1059-1071 PMID: 29034773
- Fujita KI, .et al. Involvement of the Transporters P-Glycoprotein and Breast Cancer Resistance Protein in Dermal Distribution of the Multikinase Inhibitor Regorafenib and Its Active Metabolites, J Pharm Sci, 2017, Sep;106(9):2632-2641 PMID: 28479358
- Tomoko Ogawa-Morita, .et al. Validation of a Liquid Chromatography-Tandem Mass Spectrometric Assay for Quantitative Analysis of Lenvatinib in Human Plasma, Int J Anal Chem, 2017, 2017: 2341876 PMID: 28680445
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Ecdysone

Catalog No. A10341
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Ecdysone是昆虫蜕皮激素20-羟基蜕皮激素的甾体激素，它是从前腺体分泌的。了解更多

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- Miwako Toyofuku, .et al. The plant-derived triterpenoid, cucurbitacin B, but not cucurbitacin E, inhibits the developmental transition associated with ecdysone biosynthesis in Drosophila melanogaster, J Insect Physiol, 2021, Oct;134:104294 PMID: 34389412
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Epirubicin HCl

Catalog No. A10345
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Topoisomerase II 抑制剂

Epirubicin HCl是一种可透过细胞的蒽环类抗肿瘤抗生素。它用于抑制拓扑异构酶II和DNA解旋酶活性。了解更多

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Oxaliplatin (Eloxatin)

Catalog No. A10346
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DNA/RNA Synthesis 抑制剂

Oxaliplatin (Eloxatin)是一种DNA/RNA Synthesis抑制剂，具有抗结肠癌的抗肿瘤活性。了解更多

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- Mohamed Elbadawy, .et al. Anti-cancer activity of amorphous curcumin preparation in patient-derived colorectal cancer organoids, Biomed Pharmacother, 2021, Oct;142:112043 PMID: 34411919
- Tatsuya Usui, .et al. Hedgehog Signals Mediate Anti-Cancer Drug Resistance in Three-Dimensional Primary Colorectal Cancer Organoid Culture, Int J Mol Sci, 2018, Apr; 19(4): 1098 PMID: 29642386
- Shimokawa M, .et al. Visualization and targeting of LGR5+ human colon cancer stem cells, Nature, 2017, May 11;545(7653):187-192 PMID: 28355176
- Eri Takiguchi, .et al. Growth inhibitory effect of the Src inhibitor dasatinib in combination with anticancer agents on uterine cervical adenocarcinoma cells, Exp Ther Med, 2017, Nov; 14(5): 4293-4299 PMID: 29067110
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Elvitegravir (GS-9137)

Catalog No. A10347
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HIV integrase 抑制剂

Elvitegravir (GS-9137)是一种有效的抑制剂，可抑制人类1型免疫缺陷病毒（HIV-1）整合酶介导的整合链转移步骤。了解更多

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- Lea El Khoury, .et al. Spectrometric and computational studies of the binding of HIV-1 integrase inhibitors to viral DNA extremities, PeerJ Preprints, 2019, 7:e27833v1
- El Khoury L, .et al. The inhibition process of HIV-1 integrase by diketoacids molecules: Understanding the factors governing the better efficiency of dolutegravir, Biochem Biophys Res Commun, 2017, Jul 1;488(3):433-438 PMID: 28478035
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Emodin

Catalog No. A10348
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Emodin是Rhubarb，Buckthorn 和 Japanese Knotweed (Fallopia japonica)中的一种泻药树脂，是6-甲基-1，3，8-三羟蒽醌。了解更多

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- Sakanashi M, .et al. Long-term treatment with san'o-shashin-to, a kampo medicine, markedly ameliorates cardiac ischemia-reperfusion injury in ovariectomized rats via the redox-dependent mechanism., Circ J. , 2013, 77(7):1827-37. PMID: 23615023
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Ergosterol

Catalog No. A10361
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Ergosterol是固醇和维生素D2的生物前体（一种维生素原）。了解更多

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Etoposide (VP-16)

Catalog No. A10373
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Topoisomerase II 抑制剂

Etoposide (VP-16)是通过抑制topoisomerase II活性而抑制DNA合成。了解更多

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- Reiko Watanabe, .et al. Development of an In Silico Prediction Model for P-glycoprotein Efflux Potential in Brain Capillary Endothelial Cells toward the Prediction of Brain Penetration, J Med Chem, 2021, Mar 11;64(5):2725-2738 PMID: 33619967
- Chen JC, .et al. In Vitro and In Silico Mechanistic Insights into miR-21-5p-Mediated Topoisomerase Drug Resistance in Human Colorectal Cancer Cells, Biomolecules, 2019, Sep 9;9(9) PMID: 31505885
- Takashi Azuma, .et al. Removal of pharmaceuticals in water by introduction of ozonated microbubbles, SEP PURIF TECHNOL, 2019, Apr; 212: 483-489
- Calhelha RC, .et al. Mathematical models of cytotoxic effects in endpoint tumor cell line assays: critical assessment of the application of a single parametric value as a standard criterion to quantify the dose-response effects and new unexplored proposal formats, Analyst, 2017, Oct 23;142(21):4124-4141 PMID: 28991301
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Evista (Raloxifene HCl)

Catalog No. A10375
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Evista (Raloxifene HCl)是一种口服选择性雌激素受体调节剂（SERM），对骨骼具有雌激素作用，对子宫和乳房具有抗雌激素作用。了解更多

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- Renu Sudhakar, .et al. Bazedoxifene, a Postmenopausal Drug, Acts as an Antimalarial and Inhibits Hemozoin Formation, Microbiol Spectr, 2022, Jun 29;10(3) PMID: 35616371
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EX 527 (Selisistat)

Catalog No. A10377
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SIRT1 抑制剂

EX 527 (Selisistat)是一种有效的选择性SIRT1 III类组蛋白脱乙酰基酶抑制剂，在无细胞分析中的IC50为38 nM。了解更多

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- Takeshi Nakamura, .et al. Effects of NAD+ Synthesis Levels on Sirtuin 1 Deacetylase Activity in Mammalian Cells, Shimane Journal of Medical Science, 2022, 38 (2), 59-66
- Bugga Paramesha, .et al. Sirt1 and Sirt3 Activation Improved Cardiac Function of Diabetic Rats via Modulation of Mitochondrial Function, Antioxidants (Basel), 2021, Feb 24;10(3):338 PMID: 33668369
- Wenhui Yao, .et al. Icariin ameliorates endothelial dysfunction in type 1 diabetic rats by suppressing ER stress via the PPARα/Sirt1/AMPKα pathway, J Cell Physiol, 2020, 07 August
- Guang Bai, .et al. Chapter 1 - Epigenetic Tools in Chronic Pain Studies, Epigenetics of Chronic Pain, 2019, Pages 1-48
- Yoshikawa A, .et al. Deletion of Atf6α impairs astroglial activation and enhances neuronal death following brain ischemia in mice, J Neurochem, 2015, Feb;132(3):342-53 PMID: 25351847
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Exemestane

Catalog No. A10378
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Aromatase 抑制剂

Exemestane是一种口服类固醇芳香化酶抑制剂，除绝经后妇女的手术和/或放疗外，还用于ER阳性乳腺癌。了解更多

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Ezetimibe (Zetia)

Catalog No. A10379
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Ezetimibe (Zetia)是一种有效的、选择性的胆固醇吸收抑制剂，用来降低胆固醇。了解更多

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- Nihei W, .et al. NPC1L1-dependent intestinal cholesterol absorption requires ganglioside GM3 in membrane microdomains, J Lipid Res, 2018, Nov; 59(11): 2181-2187 PMID: 30242108
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Fisetin (Fustel)

Catalog No. A10388
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Fisetin (Fustel)是有效的Sirtuin活化化合物(STAC)，可以调节Sirtuin。了解更多

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- Bih-Cheng Chen, .et al. Protective effect of Fisetin against angiotensin II-induced apoptosis by activation of IGF-IR-PI3K-Akt signaling in H9c2 cells and spontaneous hypertension rats, Phytomedicine, 2019, Apr; 57:1-8
- Jeng LB, .et al. Fisetin mediated apoptotic cell death in parental and Oxaliplatin/irinotecan resistant colorectal cancer cells in vitro and in vivo, J Cell Physiol, 2018, Sep;233(9):7134-7142 PMID: 29574877
- Kuan-Ho Lin, .et al. Bioactive flavone fisetin attenuates hypertension associated cardiac hypertrophy in H9c2 cells and in spontaneously hypertension rats, Journal of Functional Foods, 2018, 52: 212-218
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FK-506 (Tacrolimus)

Catalog No. A10389
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mTOR 抑制剂

FK-506 (Tacrolimus)是一种免疫抑制药物，通过结合到抑免蛋白FKBP12 (FK506 结合蛋白)产生新的复合物，从而降低T细胞中肽酰脯氨酰异构酶活性。了解更多

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- Ogawa Y, .et al. Inhibition of astrocytic adenosine receptor A2A attenuates microglial activation in a mouse model of Sandhoff disease, Neurobiol Dis, 2018, Oct;118:142-154 PMID: 30026035
- Yuko Okamoto, .et al. In vivo drug delivery efficiency of albumin-encapsulated liposomes as hydrophobic drug carriers, J Drug Deliv Sci Technol, 2018, 47: 62-66
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Fludarabine Phosphate (Fludara)

Catalog No. A10395
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Fludarabine Phosphate (Fludara)是一种用于治疗血液恶性肿瘤(血细胞癌，如白血病和淋巴瘤)的化疗药物。氟达拉滨通过干扰核糖核苷酸还原酶和dna聚合酶来抑制DNA合成。它对分裂细胞和静止细胞都有活性。了解更多

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Fludarabine (Fludara)

Catalog No. A10396
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STAT 抑制剂

Fludarabine或fludarabine(fludara)是一种用于治疗血液恶性肿瘤(血细胞癌，如白血病和淋巴瘤)的化疗药物。Fludarabine通过干扰核糖核苷酸还原酶和DNA聚合酶来抑制DNA合成。它对分裂细胞和静止细胞都有活性。了解更多

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- Irene Dell'Anno, .et al. Drug-repositioning screening identified fludarabine and risedronic acid as potential therapeutic compounds for malignant pleural mesothelioma, Invest New Drugs, 2020, Dec 9 PMID: 33300108
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Formononetin (Formononetol)

Catalog No. A10406
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Formononetin (Formononetol)是来自黄芪根的植物雌激素和o-甲基化异黄酮。它被用作血液增强剂，并在补充和替代药物中改善血液微循环。它通过调节ERK1/2和p38 MAPK通路促进内皮修复和伤口愈合，这一过程涉及Egr-1转录因子的过度表达。了解更多

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Fumalic acid (Ferulic acid)

Catalog No. A10411
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Fumalic acid是羟基肉桂酸和一种在阿魏或川芎中发现的有机化合物。它具有多种药理作用，如抗血小板聚集，更好地缓解前列腺的疼痛，缓解血管痉挛。了解更多

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Galanthamine hydrobromide

Catalog No. A10416
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AChE 抑制剂

Galanthamine hydrobromide是一种乙酰胆碱酯酶抑制剂，IC50为14 nM。了解更多

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Gastrodin (Gastrodine)

Catalog No. A10418
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Gastrodin (Gastrodine)是一种多酚。它是4-羟基苯甲醇(天麻素)的糖苷。了解更多

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Genistin (Genistoside)

Catalog No. A10426
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Genistin (Genistoside)是一种异黄酮，存在于许多饮食植物中，如大豆和葛根。显示出刺激体内雌激素依赖性乳腺癌细胞生长。了解更多

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- Azuma T, .et al. Distribution of six anticancer drugs and a variety of other pharmaceuticals, and their sorption onto sediments, in an urban Japanese river, Environ Sci Pollut Res Int, 2017, Aug;24(23):19021-19030 PMID: 28660504
- Azuma T, .et al. Detection of pharmaceuticals and phytochemicals together with their metabolites in hospital effluents in Japan, and their contribution to sewage treatment plant influents, Sci Total Environ, 2016, Apr 1;548-549:189-197 PMID: 26802347
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Ginkgolide B

Catalog No. A10429
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PAFR 拮抗剂

Ginkgolide B (BN 52021)是一种PAFR拮抗剂，IC50为3.6 μM。了解更多

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Glycyrrhizic acid

Catalog No. A10434
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Glycyrrhizic acid是从甘草中分离的一种广泛使用的抗炎剂。了解更多

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Gossypol

Catalog No. A10435
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dehydrogenase inhibitor

Gossypol是一种多酚醛，渗透细胞并作为几种脱氢酶的抑制剂。了解更多

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- Amy L. Farthing, .et al. Response of northern bobwhites fed single doses of gossypol, Wildlife Society Bulletin, 2018, 42(3):460-466;
- Jin Qu, .et al. Gossypol potentiates carboplatin effects against ovarian cancer, Biomed Res, 2017, 28 (8): 3355-3361
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Gramine

Catalog No. A10436
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Gramine是存在于几种植物中的天然吲哚生物碱。禾本科植物可能在这些植物中起防御作用，因为它对许多生物体有毒。它主要用于合成有机化学，作为色氨酸合成的起始原料。了解更多

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- Elizabeth Read, .et al. Changes in field concentrations of five phalaris alkaloids and their association with toxicity in pastures of Victoria, Australia, Crop and Pasture Science, 2020, 71(4), 389-400
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GSK1292263

Catalog No. A10439
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GPR119 激动剂

GSK-1292263是一种新型GPR119激动剂。了解更多

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- Inoue A, .et al. Illuminating G-Protein-Coupling Selectivity of GPCRs, Cell, 2019, Jun 13;177(7):1933-1947 PMID: 31160049
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GSK429286A

Catalog No. A10441
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ROCK 抑制剂

GSK429286A是含有蛋白激酶(ROCK)的Rho相关卷曲螺旋的细胞渗透性选择性小分子抑制剂。了解更多

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Hesperetin

Catalog No. A10449
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PDE4 抑制剂

Hesperetin是一种选择性磷酸二酯酶(PDE)4抑制剂，存在于中药“陈皮”中。橙皮素是一种柑橘类黄酮，据报道可以降低血浆胆固醇。橙皮素降低Hep-G2细胞中ACAT-2 mRNA的转录，并以剂量依赖的方式降低ApoB蛋白的合成。它也是类癌的潜在疗法。了解更多

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Hesperidin

Catalog No. A10450
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Hesperidin是一种黄酮苷，大量存在于柑橘类水果中。了解更多

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Honokiol

Catalog No. A10453
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Antiangiogenic and Antitumor Agent

Honokiol是存在于广玉兰的球果、树皮和叶子中的木脂素，在黑色素瘤、肉瘤、骨髓瘤、白血病、膀胱、肺、前列腺、口腔鳞状细胞癌和结肠癌细胞系中显示促凋亡作用。了解更多

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Indocyanine green

Catalog No. A10472
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Indocyanine green是一种用于医学诊断的菁染料。它用于测定心输出量、肝功能和肝血流量，以及眼科血管造影术。了解更多

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- Adrian Rosenberg, .et al. Real-Time Fluorescence Imaging Using Indocyanine Green to Assess Therapeutic Effects of Near-Infrared Photoimmunotherapy in Tumor Model Mice, Mol Imaging, 2020, Jan-Dec; 19: 1536012120934965 PMID: 32609570
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Indole-3-carbinol

Catalog No. A10473
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Indole-3-carbinol是由芥子油苷葡糖芸苔素苷分解产生的，芥子油苷在十字花科蔬菜中含量相对较高。了解更多

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Irbesartan (Avapro)

Catalog No. A10477
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AT1 拮抗剂

Irbesartan (Avapro)是一种血管紧张素II受体拮抗剂，IC50为1.3 nM，主要用于治疗高血压。了解更多

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Irinotecan

Catalog No. A10478
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Topoisomerase I 抑制剂

Irinotecan通过抑制拓扑异构酶防止DNA解链。了解更多

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- Gils Jose, .et al. Co-Delivery of CPT-11 and Panobinostat with Anti-GD2 Antibody Conjugated Immunoliposomes for Targeted Combination Chemotherapy, Cancers (Basel), 2020, Oct 31;12(11):E3211 PMID: 33142721
- T Kannathasan, .et al. Chemoresistance-Associated Silencing of miR-4454 Promotes Colorectal Cancer Aggression through the GNL3L and NF-κB Pathway, Cancers (Basel), 2020, May; 12(5): 1231 PMID: 32422901
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JNJ 26854165

Catalog No. A10491
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p53 activator

JNJ-26854165是P53激活剂之一，与AraC或阿霉素协同作用，诱导P53介导的凋亡，可能为急性白血病的治疗提供新的治疗途径。了解更多

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- Chang SJ, .et al. Proteomic investigating the cooperative lethal effect of EGFR and MDM2 inhibitors on ovarian carcinoma, Arch Biochem Biophys, 2018, Jun 1;647:10-32 PMID: 29655550
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Ki8751

Catalog No. A10502
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VEGFR-2 抑制剂

ki8751是一种细胞可渗透的喹啉氧基苯基脲化合物，在基于细胞和无细胞的检测中起Flk-1 (VEGFR-2)选择性抑制剂的作用。了解更多

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- Kohei Ashina, .et al. VEGF-induced blood flow increase causes vascular hyper-permeability in vivo, Biochem Biophys Res Commun, 2015, Aug 21;464(2):590-5 PMID: 26163262
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Kinetin

Catalog No. A10503
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Kinetin是一种细胞分裂素，一种促进细胞分裂的植物激素。了解更多

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KU-60019

Catalog No. A10507
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ATM 抑制剂

KU-60019是一种强效特异性ATM抑制剂，IC50为6.3 nM。了解更多

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- Fu-Xing Gong, .et al. De-dimerization of PTB is catalyzed by PDI and is involved in the regulation of p53 translation, Nucleic Acids Res, 2021, Sep 20;49(16):9342-9352 PMID: 34403458
- Hegedus C, .et al. PARP1 Inhibition Augments UVB-Mediated Mitochondrial Changes-Implications for UV-Induced DNA Repair and Photocarcinogenesis, Cancers (Basel), 2019, Dec 18;12(1) PMID: 31861350
- Masaya Igase, .et al. Combination Therapy with Reovirus and ATM Inhibitor Enhances Cell Death and Virus Replication in Canine Melanoma, Mol Ther Oncolytics, 2019, vol 15 PMID: 31650025
- CHENGHUA LOU, .et al. Targeting the ataxia telangiectasia mutated pathway for effective therapy against hirsutine-resistant breast cancer cells, Oncol Lett, 2016, Jul; 12(1): 295-300 PMID: 27347141
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L(+)-Rhamnose Monohydrate

Catalog No. A10509
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L(+)-Rhamnose (Rham) 是一种天然脱氧糖。它可以分为甲基戊糖或6-脱氧己糖。了解更多

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LAQ824 (NVP-LAQ824, Dacinostat)

Catalog No. A10516
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HDAC 抑制剂

LAQ824 (NVP-LAQ824)是一种有效的新型组蛋白去乙酰化酶抑制剂，具有显著的抗多发性骨髓瘤活性。了解更多

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- De-Run Chen, .et al. Engineered nanogels simultaneously implement HDAC inhibition and chemotherapy to boost antitumor immunity via pyroptosis, Appl Mater Today, 2022, 26: 101363

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