你的浏览器似乎禁用了 JavaScript。
您必须在浏览器中启用JavaScript才能使用本网站的功能。

微信关注
申请试用装

主页 /
Products On Sale

Products On Sale

Quick View
Olanzapine (LY170053)

Catalog No. A10667
Quick View

添加到收藏
5-HT Receptors/D2 dopamine receptor 拮抗剂

Olanzapine (LY170053)对5-HT2血清素和D2多巴胺受体拮抗剂具有高亲和力。了解更多

Bulk Inquiry Free Sample
Quick View
BX471

Catalog No. A14409
Quick View

添加到收藏
CCR1 拮抗剂

BX471是一种有效的选择性非肽CCR1拮抗剂（对于人CCR1，Ki = 1 nM），对CCR1的选择性是CCR2，CCR5和CXCR4的250倍。了解更多

Bulk Inquiry
Quick View
FTY720 (Fingolimod)

Catalog No. A10408
Quick View

添加到收藏
S1P Receptor 拮抗剂

FTY720 (Fingolimod)是ISP-1(肉豆蔻酸)的衍生物，ISP-1是中国草药Iscaria sinclarii的真菌代谢物，也是鞘氨醇的结构类似物。了解更多

Product Citations (5)

Bulk Inquiry
- Tina Sepasi, .et al. Targeted gene delivery to the brain using CDX-modified chitosan nanoparticles, BioImpacts, 2022, 28 May
- Zengzi Zhou, .et al. Effects of immunomodulatory drug Fingolimod (FTY720) on Chlamydia dissemination and pathogenesis, Infect Immun, 2020, Oct 19;88(11):e00281-20 PMID: 32868341
- Mayu Idehara, .et al. Inulooligosaccharides in Atractylodis lanceae rhizoma and Atractylodis rhizoma of hochuekkito formula are essential for regulation of the pulmonary immune system of immuno-compromised mice, Traditional & Kampo Medicine, 2020, 22 July
- Luwa Yuan, .et al. 14-3-3 signal adaptor and scaffold proteins mediate GPCR trafficking, Sci Rep, 2019, 9:11156 PMID: 31371790
- Sakai Y, .et al. Peyer's patch-immunomodulating glucans from sugar cane enhance protective immunity through stimulation of the hemopoietic system, Int J Biol Macromol, 2018, Nov 22;124:505-514 PMID: 30471397
Quick View
A 740003

Catalog No. A11316
Quick View

添加到收藏
P2X7 receptor 拮抗剂

A740003是P2X7受体的新型竞争性拮抗剂（人的IC50值= 40 nM，大鼠的IC50值= 18 nM）。了解更多

Bulk Inquiry Free Sample
Quick View
NBQX

Catalog No. A13109
Quick View

添加到收藏
AMPA Receptor 拮抗剂

NBQX是一种有效，选择性和竞争性的AMPA受体拮抗剂。了解更多

Bulk Inquiry
Quick View
Clozapine N-oxide

Catalog No. A15048
Quick View

添加到收藏
5-HT1C receptor 拮抗剂

Clozapine N-oxide是氯氮平的主要代谢产物，在体外可降低SR-2A（5-HT2血清素受体）密度。了解更多

Bulk Inquiry Free Sample
Quick View
Candesartan (Atacand)

Catalog No. A10175
Quick View

添加到收藏
RAAS 拮抗剂

Candesartan (Atacand)是一种血管紧张素受体阻滞剂（也称为血管紧张素II受体拮抗剂或AIIRA）。了解更多

Product Citations (3)

Bulk Inquiry Free Sample
- Hideki Kobara, .et al. Antihypertensive drug telmisartan inhibits cell proliferation of gastrointestinal stromal tumor cells in vitro, Molecular Medicine Reports, 2020, 22(2)
- Dao-Lai Zhang, .et al. Gq activity- and β-arrestin-1 scaffolding-mediated ADGRG2/CFTR coupling are required for male fertility, eLife, 2018, 7: e33432 PMID: 29393851
- Toshihide Kashihara, .et al. Angiotensin II activates CaV1.2 Ca2+ channels through β‐arrestin2 and casein kinase 2 in mouse immature cardiomyocytes, J Physiol, 2017, Jul 1; 595(13): 4207-4225 PMID: 28295363
Quick View
LCL-161

Catalog No. A11928
Quick View

添加到收藏
拮抗剂of IAPs抑制剂

LCL161是口服生物可利用的第二个线粒体衍生的半胱天冬酶（SMAC）类似物激活剂，也是IAP（细胞凋亡抑制蛋白）家族蛋白的抑制剂，具有潜在的抗肿瘤活性，抑制 HEK293 细胞中 XIAP 和 MDA-MB-231细胞中 cIAP1 的 IC50分别为 35 和 0.4 nM。了解更多

Product Citations (7)

Bulk Inquiry Free Sample
- Han-Hee Park, .et al. RIPK3 activation induces TRIM28 derepression in cancer cells and enhances the anti-tumor microenvironment, Mol Cancer, 2021, Aug 21;20(1):107 PMID: 34419074
- Se-Yeon Park, .et al. Reduction in MLKL-mediated endosomal trafficking enhances the TRAIL-DR4/5 signal to increase cancer cell death, Cell Death & Disease, 2020, 11:744 PMID: 32917855
- J Chen, .et al. Interferon-γ induces the cell surface exposure of phosphatidylserine by activating MLKL in the absence of caspase-8 activity, JBC, 2019, June PMID: 31217278
- Choi SW, .et al. PELI1 Selectively Targets Kinase-Active RIP3 for Ubiquitylation-Dependent Proteasomal Degradation, Mol Cell, 2018, Jun 7;70(5):920-935.e7 PMID: 29883609
- Han-Hee Park, .et al. HS-1371, a novel kinase inhibitor of RIP3-mediated necroptosis, Exp Mol Med, 2018, Sep; 50(9): 125 PMID: 30237400
- Gi-Bang Koo, .et al. Methylation-dependent loss of RIP3 expression in cancer represses programmed necrosis in response to chemotherapeutics, Cell Res, 2015, Jun; 25(6): 707-725 PMID: 25952668
- Kim SK, .et al. Upregulated RIP3 Expression Potentiates MLKL Phosphorylation-Mediated Programmed Necrosis in Toxic Epidermal Necrolysis, J Invest Dermatol, 2015, Aug;135(8):2021-2030 PMID: 25748555
Quick View
StemRegenin 1 (SR1)

Catalog No. A12945
Quick View

添加到收藏
AhR 拮抗剂

StemRegenin 1 (SR1)是一种细胞可渗透的嘌呤衍生物，作为芳香烃受体的拮抗剂，促进造血干细胞(HSC)的自我更新。了解更多

Bulk Inquiry Free Sample
Quick View
Ziprasidone

Catalog No. A15286
Quick View

添加到收藏
5-HT/dopamine receptor 拮抗剂

Ziprasidone是5-HT（5-羟色胺）和多巴胺受体拮抗剂的组合，具有抗精神病活性。了解更多

Bulk Inquiry Free Sample
Quick View
Fesoterodine fumarate (Toviaz)

Catalog No. A10386
Quick View

添加到收藏
AChR 拮抗剂

Fesoterodine fumarate是一种用于尿急的药物，可减少尿液通过的频率并促使尿失禁。了解更多

Bulk Inquiry Free Sample
Quick View
TCN 201

Catalog No. A11947
Quick View

添加到收藏
NMDA Receptor 拮抗剂

TCN 201是对NR1/NR2A相对于含NR1/NR2B的受体具有选择性的NMDA受体拮抗剂。了解更多

Bulk Inquiry Free Sample
Quick View
cis-(Z)-Flupentixol dihydrochloride

Catalog No. A12347
Quick View

添加到收藏
Dopamine receptor 拮抗剂

cis-(Z)-Flupentixol dihydrochloride是多巴胺受体拮抗剂、抗精神病药物、抗精神病药物。了解更多

Bulk Inquiry Free Sample
Quick View
ODM-201

Catalog No. A15797
Quick View

添加到收藏
Androgen receptor 拮抗剂

ODM-201是一种有效且完全的人类AR（hAR）拮抗剂，IC50值为26 nM。了解更多

Bulk Inquiry Free Sample
Quick View
WAY-100635

Catalog No. A11182
Quick View

添加到收藏
5HT1A 拮抗剂

WAY-100635最初被认为是选择性的5-HT1A受体拮抗剂，但随后的研究表明它也可作为D4受体的有效全效激动剂。了解更多

Bulk Inquiry Free Sample
Quick View
Ketanserin (Vulketan Gel)

Catalog No. A10497
Quick View

添加到收藏
5-HT2A serotonin receptor 拮抗剂

Ketanserin (Vulketan Gel)是大鼠和人5-HT2A血清素受体拮抗剂，Ki为2.5 nM。了解更多

Bulk Inquiry Free Sample
Quick View
Tandospirone

Catalog No. A13293
Quick View

添加到收藏
5-HT Receptor 拮抗剂

Tandospirone是5HT1A受体的部分激动剂。它以剂量依赖性方式显着降低氟哌啶醇诱导的运动迟缓。了解更多

Bulk Inquiry Free Sample
Quick View
BH3I-1

Catalog No. A16061
Quick View

添加到收藏
Bcl-XL 拮抗剂

BH3I-1是Bcl-XL-BH3 domain interaction抑制剂，Ki值为2.4 μM。它是一种Bcl-2家族蛋白的选择性抑制剂。了解更多

Bulk Inquiry Free Sample
Quick View
Irbesartan (Avapro)

Catalog No. A10477
Quick View

添加到收藏
AT1 拮抗剂

Irbesartan (Avapro)是一种血管紧张素II受体拮抗剂，IC50为1.3 nM，主要用于治疗高血压。了解更多

Bulk Inquiry Free Sample
Quick View
Phenoxybenzamine hydrochloride

Catalog No. A10719
Quick View

添加到收藏
α-adrenergic (AR) 拮抗剂/CaM 抑制剂

Phenoxybenzamine hydrochloride是一种细胞可渗透的，非特异性的，不可逆的α-肾上腺素（AR）拮抗剂，也可作为CaM抑制剂。了解更多

Bulk Inquiry Free Sample
Quick View
Rolapitant

Catalog No. A13680
Quick View

添加到收藏
NK1 receptor 拮抗剂

Rolapitant，也称为SCH-619734，是一种选择性的，可生物利用的CNS渗透性神经激肽NK1受体拮抗剂，在呕吐动物模型中显示出行为效应。了解更多

Product Citations (1)

Bulk Inquiry Free Sample
- Bubak AN, .et al. Varicella Zoster Virus Induces Nuclear Translocation of the Neurokinin-1 Receptor, Promoting Lamellipodia Formation and Viral Spread in Spinal Astrocytes, J Infect Dis, 2018, Sep 8;218(8):1324-1335 PMID: 29788447
Quick View
Ambrisentan (BSF 208075)

Catalog No. A11291
Quick View

添加到收藏
EndothelinA receptor 拮抗剂

Ambrisentan (BSF 208075)充当内皮素受体拮抗剂，对A型内皮素受体（ETA）具有选择性。了解更多

Product Citations (3)

Bulk Inquiry Free Sample
- Naoki Dohi, .et al. Quantitative real-time measurement of endothelin-1-induced contraction in single non-activated hepatic stellate cells, PLoS One, 2021, 16(8): e0255656 PMID: 34343209
- Tony Ngo, .et al. Orphan receptor ligand discovery by pickpocketing pharmacological neighbors, Nat Chem Biol, 2017, Feb; 13(2): 235-242 PMID: 27992882
- Toshiaki Okamoto, .et al. Antifibrotic effects of ambrisentan, an endothelin-A receptor antagonist, in a non-alcoholic steatohepatitis mouse model, World J Hepatol, 2016, Aug 8; 8(22): 933-941 PMID: 27574547
Quick View
Vorapaxar (SCH 530348)

Catalog No. A12832
Quick View

添加到收藏
PAR-1 拮抗剂

Vorapaxar (SCH 530348)是一种有效的口服活性凝血酶受体（PAR-1）拮抗剂，Ki为8.1 nM。了解更多

Product Citations (6)

Bulk Inquiry Free Sample
- Cansu Tekin, .et al. Macrophage-secreted MMP9 induces mesenchymal transition in pancreatic cancer cells via PAR1 activation, Cell Oncol (Dordr), 2020, Aug 18 PMID: 32809114
- Cansu Tekin, .et al. PAR1 signaling on tumor cells limits tumor growth by maintaining a mesenchymal phenotype in pancreatic cancer, Oncotarget, 2018, Aug 10; 9(62): 32010-32023 PMID: 30174793
- Claushuis TA, .et al. Thrombin contributes to protective immunity in pneumonia-derived sepsis via fibrin polymerization and platelet-neutrophil interactions, J Thromb Haemost, 2017, Apr;15(4):744-757 PMID: 28092405
- Maaike Waasdorp, .et al. Plasmin reduces fibronectin deposition by mesangial cells in a protease-activated receptor-1 independent manner, Biochem Biophys Rep, 2017, Jul; 10: 152-156 PMID: 29114573
- Joseph C. Mudd, .et al. Inflammatory Function of CX3CR1+ CD8+ T Cells in Treated HIV Infection Is Modulated by Platelet Interactions, J Infect Dis, 2016, Dec 15; 214(12): 1808-1816 PMID: 27703039
- Corey E. Tabit, .et al. Elevated Angiopoietin-2 Level in Patients With Continuous-Flow Left Ventricular Assist Devices Leads to Altered Angiogenesis and Is Associated With Higher Non-Surgical Bleeding, Circulation, 2016, Jul 12; 134(2): 141-152 PMID: 27354285
Quick View
Labetalol HCl

Catalog No. A14239
Quick View

添加到收藏
alpha1/beta adrenergic receptors 拮抗剂

Labetalol HCl是选择性α1-肾上腺素能受体和非选择性β-肾上腺素能受体的双重拮抗剂。了解更多

Product Citations (1)

Bulk Inquiry Free Sample
- Reiko Watanabe, .et al. Development of an In Silico Prediction Model for P-glycoprotein Efflux Potential in Brain Capillary Endothelial Cells toward the Prediction of Brain Penetration, J Med Chem, 2021, Mar 11;64(5):2725-2738 PMID: 33619967
Quick View
Imatinib (Gleevec)

Catalog No. A10259
Quick View

添加到收藏
PDGFR 抑制剂

Imatinib (Gleevec)是一种多靶点酪氨酸激酶抑制剂，抑制v-Abl、c-Kit和PDGFR的IC50分别为0.6，0.1和0.1 μM。了解更多

Product Citations (6)

Bulk Inquiry Free Sample
- Aya Hasan Alshammari, .et al. Discrimination of hand-foot skin reaction caused by tyrosine kinase inhibitors based on direct keratinocyte toxicity and vascular endothelial growth factor receptor-2 inhibition, Biochem Pharmacol, 2022, Mar;197:114914 PMID: 35041812
- Takafumi Shima, .et al. Glucose transporter-1 inhibition overcomes imatinib resistance in gastrointestinal stromal tumor cells, Oncol Rep, 2022, 47: 7 PMID: 34738628
- Reiko Watanabe, .et al. Development of an In Silico Prediction Model for P-glycoprotein Efflux Potential in Brain Capillary Endothelial Cells toward the Prediction of Brain Penetration, J Med Chem, 2021, Mar 11;64(5):2725-2738 PMID: 33619967
- BM Duggan, .et al. RIPK2 Dictates Insulin Responses to Tyrosine Kinase Inhibitors in Obese Male Mice, Endocrinology, 2020, May 30;bqaa086 PMID: 32473019
- Li Li, .et al. Evidence for activated Lck protein tyrosine kinase as the driver of proliferation in acute myeloid leukemia cell, CTV-1, Leukemia Res, 2019, 78:12-20 PMID: 30660961
- Brittany M. Duggan, .et al. Tyrosine kinase inhibitors of Ripk2 attenuate bacterial cell wall-mediated lipolysis, inflammation and dysglycemia, Sci Rep, 2017, 7: 1578 PMID: 28484277
Quick View
AMD 070

Catalog No. A11315
Quick View

添加到收藏
CXCR4 拮抗剂

AMD 070是CXCR4趋化因子受体拮抗剂。了解更多

Product Citations (2)

Bulk Inquiry Free Sample
- Uchida D, .et al. Effect of a novel orally bioavailable CXCR4 inhibitor, AMD070, on the metastasis of oral cancer cells, Oncol Rep, 2018, Jul;40(1):303-308 PMID: 29749473
- Mamoru Morimoto, .et al. Enhancement of the CXCL12/CXCR4 axis due to acquisition of resistance in pancreatic cancer: effect of CXCR4 antagonists, BMC Cancer, 2016, 16: 305 PMID: 27175473
Quick View
GSK-3787

Catalog No. A12391
Quick View

添加到收藏
PPAR 拮抗剂

GSK-3787是一种有效的选择性过氧化物酶体增殖物激活受体δ（PPARδ）拮抗剂（pIC50 = 6.6）。了解更多

Bulk Inquiry Free Sample
Quick View
PD 123319 ditrifluoroacetate

Catalog No. A13201
Quick View

添加到收藏
angiotensin AT2 receptor 拮抗剂

PD 123319 ditrifluoroacetate是一种有效的，选择性的非肽血管紧张素AT2受体拮抗剂。大鼠肾上腺组织和大脑的IC50值分别为34和210 nM。了解更多

Product Citations (1)

Bulk Inquiry Free Sample
- Dao-Lai Zhang, .et al. Gq activity- and β-arrestin-1 scaffolding-mediated ADGRG2/CFTR coupling are required for male fertility, eLife, 2018, 7: e33432 PMID: 29393851
Quick View
Netupitant

Catalog No. A14428
Quick View

添加到收藏
NK1 receptor 拮抗剂

Netupitant是一种选择性的神经激肽1（NK1）受体拮抗剂。它竞争性地结合并阻断中枢神经系统（CNS）中人类物质P/NK1受体的活性，从而抑制内源性速激肽神经肽物质P（SP）的NK1受体结合，这可能导致预防化疗引起的恶心和呕吐（CINV）。了解更多

Bulk Inquiry
Quick View
Vicriviroc Malate

Catalog No. A10971
Quick View

添加到收藏
CCR5 拮抗剂

Vicriviroc Malate是CCR5拮抗剂，也是HIV-1进入靶细胞的有效抑制剂，对HIV分离株的平均IC50 = 0.46 nM，IC50 = 1?10 nM（n = 52）。了解更多

Product Citations (1)

Bulk Inquiry Free Sample
- Tomohiro Nabekura, .et al. Effects of Antiviral Drugs on Organic Anion Transport in Human Placental BeWo Cells, Antimicrob Agents Chemother, 2015, Dec; 59(12): 7666-7670 PMID: 26416870
Quick View
17 alpha-propionate

Catalog No. A10009
Quick View

添加到收藏
Androgen 拮抗剂

17 alpha-propionate是一种新型的局部和外周选择性雄激素拮抗剂。了解更多

Bulk Inquiry Free Sample
Quick View
Telmisartan

Catalog No. A10905
Quick View

添加到收藏
AT1 拮抗剂

Telmisartan是一种抑制血管紧张素II AT1受体的血管紧张素II受体拮抗剂。了解更多

Bulk Inquiry Free Sample
Quick View
Umeclidinium bromide

Catalog No. A15268
Quick View

添加到收藏
Muscarinic receptor 拮抗剂

Umeclidinium bromide (GSK573719A)是毒蕈碱受体拮抗剂，可用于治疗慢性阻塞性肺疾病（COPD）。了解更多

Bulk Inquiry
Quick View
LDE225 (NVP-LDE225, Sonidegib)

Catalog No. A10520
Quick View

添加到收藏
Smo 拮抗剂

LDE225 (NVP-LDE225)是一种强效、选择性和口服生物可利用的平滑(SMO)拮抗剂，通过平滑受体(SMO)的拮抗作用抑制hedgehog (Hh)信号通路。了解更多

Product Citations (1)

Bulk Inquiry Free Sample
- Daniel Doheny, .et al. Combined inhibition of JAK2-STAT3 and SMO-GLI1/tGLI1 pathways suppresses breast cancer stem cells, tumor growth, and metastasis, Oncogene, 2020, Oct;39(42):6589-6605 PMID: 32929154
Quick View
Proparacaine HCl

Catalog No. A11715
Quick View

添加到收藏
Voltage-gated sodium channels 拮抗剂

Proparacaine HCl是一种电压门控钠通道拮抗剂，ED50为3.4 mM。了解更多

Bulk Inquiry Free Sample
Quick View
N-Desmethylclozapine

Catalog No. A13762
Quick View

添加到收藏
5-HT2C serotonin receptor 拮抗剂

N-Desmethylclozapine是一种有效的选择性5-HT2C血清素受体拮抗剂。了解更多

Bulk Inquiry Free Sample
Quick View
Macitentan

Catalog No. A11492
Quick View

添加到收藏
Endothelin receptor 拮抗剂

Macitentan是一种口服活性非肽双重ETA/ETB(内皮素) receptor双重拮抗剂，IC50为0.5 nM/391 nM。用于治疗特发性肺纤维化(IPF)和肺动脉高压(PAH)。了解更多

Bulk Inquiry
Quick View
RS-127445

Catalog No. A11165
Quick View

添加到收藏
5-HT2B receptor 拮抗剂

RS-127445是5-羟色胺5-HT2B受体的有效和选择性拮抗剂，相对于密切相关的5-HT2A和5-HT2C受体具有约1000倍的选择性。了解更多

Product Citations (1)

Bulk Inquiry Free Sample
- Takeshi Takayanagi, .et al. Serotonin 5-HT2B receptor antagonism is fundamental for protecting PC12 cells exposed to hydrogen peroxide, Fujita Medical Journal, 2015, 1(1), 1-5, 2015
Quick View
Asenapine maleate

Catalog No. A10091
Quick View

添加到收藏
H1 拮抗剂

Asenapine maleate平对多种受体具有高亲和力（pKi），包括5-羟色胺5-HT1A（8.6），5-HT1B（8.4），5-HT2A（10.2），5-HT2B（9.8），5-HT2C（10.5），5 -HT5A（8.8），5-HT6（9.5）和5-HT7（9.9）受体，肾上腺素α1（8.9），α2A（8.9），α2B（9.5）和α2C（8.9）受体，多巴胺D1（ 8.9），D2（8.9），D3（9.4）和D4（9.0）受体以及组胺H1（9.0）和H2（8.2）受体。了解更多

Product Citations (1)

Bulk Inquiry Free Sample
- Keisuke Obara, .et al. Inhibitory Effects of Antipsychotics on the Contractile Response to Acetylcholine in Rat Urinary Bladder Smooth Muscles, Biol Pharm Bull, 2021, 44, 1140-1150
Quick View
AM251

Catalog No. A12914
Quick View

添加到收藏
CB1 receptor 拮抗剂

AM251是有效的CB1受体拮抗剂（IC50 = 8 nM，Ki = 7.49 nM），其选择性是CB2受体的306倍。了解更多

Product Citations (1)

Bulk Inquiry Free Sample
- Potential for pharmacological manipulation of human embryonic stem cells. Br J Pharmacol. 2013 May; 169(2): 269–289.
Quick View
MK-571

Catalog No. A12529
Quick View

添加到收藏
CysLT1 receptor 拮抗剂

MK-571是有效的CysLT1（LTD4）白三烯受体反向激动剂，EC50值为1.3 nM。了解更多

Product Citations (1)

Bulk Inquiry Free Sample
- Jung-Hung Chen, .et al. Transplacental transfer of acetaminophen in pregnant rats, Biomed Pharmacother, 2022, Oct;154:113613 PMID: 36058146
Quick View
Eprosartan

Catalog No. A11121
Quick View

添加到收藏
AT1 receptor 拮抗剂

Eprosartan是一种用于治疗高血压的血管紧张素II受体拮抗剂。了解更多

Bulk Inquiry Free Sample
Quick View
Gallamine triethiodide

Catalog No. A10417
Quick View

添加到收藏
mAChR M2 拮抗剂

Gallamine Triethiodide是一种具有显著心脏选择性的mAChR M2拮抗剂。了解更多

Bulk Inquiry Free Sample
Quick View
Tasosartan

Catalog No. A10891
Quick View

添加到收藏
Angiotensin II receptor 拮抗剂

Tasosartan是一种血管紧张素II受体拮抗剂。了解更多

Bulk Inquiry Free Sample
Quick View
Flavoxate

Catalog No. A12900
Quick View

添加到收藏
muscarinic AChR antagonist

Flavoxate结合并抑制毒蕈碱受体，从而通过改变脑干的排尿中心来抑制排尿反射并增加膀胱容量。了解更多

Bulk Inquiry
Quick View
Tolterodine tartrate (Detrol LA)

Catalog No. A10937
Quick View

添加到收藏
muscarinic receptor 拮抗剂

Tolterodine tartrate (Detrol LA)是毒蕈碱受体拮抗剂。了解更多

Bulk Inquiry Free Sample
Quick View
Tolvaptan

Catalog No. A11594
Quick View

添加到收藏
vasopressin receptor 2 拮抗剂

Tolvaptan是一种选择性的竞争性精氨酸加压素受体2拮抗剂，IC50为1.28μM。了解更多

Bulk Inquiry Free Sample
Quick View
GDC-0152

Catalog No. A14135
Quick View

添加到收藏
IAP 拮抗剂

GDC-0152是caspases（Smac）的第二个线粒体激活物，具有潜在的抗肿瘤活性。了解更多

Bulk Inquiry Free Sample
Quick View
Flupirtine maleate

Catalog No. A10251
Quick View

添加到收藏
NMDA 拮抗剂

Flupirtine maleate是Flupirine的盐形式，是一种非阿片类中枢性镇痛药，是一种选择性的神经元钾离子通道开放剂，也具有NMDA受体拮抗剂特性。了解更多

Bulk Inquiry Free Sample
Quick View
Plerixafor 8HCl (DB06809)

Catalog No. A10913
Quick View

添加到收藏
CXCR4 拮抗剂

Plerixafor 8HCl (DB06809)是CXCR4趋化因子受体拮抗剂，作用于CXCR4和CXCL12介导调节的趋化性， IC50分别为44 nM和5.7 nM。了解更多

Product Citations (3)

Bulk Inquiry Free Sample
- Mei Zheng, .et al. CXCL12 inhibits hair growth through CXCR4, Biomed Pharmacother, 2022, Jun;150:112996 PMID: 35462338
- Asiedu KO, .et al. Bone marrow cell homing to sites of acute tibial fracture: 89Zr-oxine cell labeling with positron emission tomographic imaging in a mouse model, EJNMMI Res, 2018, Dec 13;8(1):109 PMID: 30547233
- Kingsley O. Asiedu, .et al. Bone marrow cell trafficking analyzed by 89Zr-oxine positron emission tomography in a murine transplantation model, Clin Cancer Res, 2017, Jun 1; 23(11): 2759-2768 PMID: 27965305

联系我们

Not your Region? View all Distributors

溶液配制计算器

分子量计算器

稀释计算器

摩尔浓度计算器

ADOOQ 产品质量保证

Guaranteed product quality, 365 days Unconditional Return & Replacement

We promise all products to perform as described.