你的浏览器似乎禁用了 JavaScript。
您必须在浏览器中启用JavaScript才能使用本网站的功能。

微信关注
申请试用装

主页 /
Products On Sale

Products On Sale

Quick View
TRAM-34

Catalog No. A12783
Quick View

添加到收藏
Potassium Channel Blocker

TRAM-34是中等电导Ca2+激活的K+通道（KCa3.1）（Kd = 20 nM）的高度选择性阻滞剂。在KV，BKCa，KCa2，Na+，CRAC和Cl-通道上具有200-1500倍的选择性。抑制有丝分裂刺激对淋巴细胞的激活。了解更多

Product Citations (2)

Bulk Inquiry Free Sample
- Samuel Drinkall, .et al. The two pore potassium channel THIK-1 regulates NLRP3 inflammasome activation, Glia, 2022, Jul;70(7):1301-1316 PMID: 35353387
- Cheong Hoon Seo, .et al. Altered K Ca 3.1 expression following burn injury and the therapeutic potential of TRAM-34 in post-burn hypertrophic scar formation, Transl Res, 2021, Apr 24 PMID: 33905948
Quick View
Berbamine

Catalog No. A14794
Quick View

添加到收藏
Calcium channel blocker

Berbamine是钙通道阻滞剂。了解更多

Bulk Inquiry Free Sample
Quick View
A 803467

Catalog No. A11234
Quick View

添加到收藏
Sodium channel Blocker

A 803467是NaV1.8通道的选择性阻滞剂（hNaV1.8，hNaV1.3，hNaV1.7，hNaV1.5和hNaV1.2通道的IC50值分别为8、2450、6740、7340和7380 nM）。了解更多

Bulk Inquiry Free Sample
Quick View
Isradipine

Catalog No. A10487
Quick View

添加到收藏
calcium channel blocker

伊拉地平是二氢吡啶类钙通道阻滞剂。了解更多

Product Citations (1)

Bulk Inquiry Free Sample
- Deborah A. Goldspink, .et al. Mechanistic insights into the detection of free fatty and bile acids by ileal glucagon-like peptide-1 secreting cells, Mol Metab, 2018, Jan; 7: 90-101 PMID: 29167062
Quick View
A 967079

Catalog No. A12353
Quick View

添加到收藏
TRPA1 channel blocker

A 967079是选择性TRPA1通道阻滞剂(人和大鼠TRPA1受体的IC50值分别为67和289 nM)。了解更多

Product Citations (2)

Bulk Inquiry Free Sample
- L Jin, .et al. Acrolein but not its metabolite, 3-Hydroxypropylmercapturic acid (3HPMA), activates vascular transient receptor potential Ankyrin-1 (TRPA1): Physiological to toxicological implications, Toxicol Appl Pharmacol, 2021, Jul 13;426:115647 PMID: 34271065
- L. Jin, .et al. Crotonaldehyde-induced vascular relaxation and toxicity: Role of endothelium and transient receptor potential ankyrin-1 (TRPA1), Toxicology and Applied Pharmacology, 2020, 398(1),
Quick View
QX 314 chloride

Catalog No. A13760
Quick View

添加到收藏
Sodium channel Blocker

QX 314 chloride是利多卡因的膜不可渗透的季衍生物，一种电压激活的Na+通道阻滞剂。了解更多

Bulk Inquiry Free Sample
Quick View
Vernakalant HCl

Catalog No. A15275
Quick View

添加到收藏
Ion channel blocker

Vernakalant hydrochloride是一种研究性混合离子通道阻滞剂，可以以2至5 mg/kg的剂量终止人的急性心房纤颤（AF），并且与现有药物相比，对房颤的选择性更高。在抗心律不齐的治疗中。了解更多

Product Citations (1)

Bulk Inquiry Free Sample
- Joe Z.Zhang, .et al. A Human iPSC Double-Reporter System Enables Purification of Cardiac Lineage Subpopulations with Distinct Function and Drug Response Profiles, Cell Stem Cell, 2019, 24, 1-10
Quick View
Bisoprolol fumarate

Catalog No. A10149
Quick View

添加到收藏
β1 adrenergic receptor blocker

Bisoprolol fumarate是一种属于β受体阻滞剂的药物，β受体阻滞剂是一类主要用于心血管疾病的药物。更具体地说，它是一种选择性的β1肾上腺素能受体阻滞剂。了解更多

Bulk Inquiry Free Sample
Quick View
Orphenadrine citrate

Catalog No. A11712
Quick View

添加到收藏
NMDA receptor 拮抗剂

Orphenadrine柠檬酸盐是NMDA受体拮抗剂，Ki为6.0μM，还是HERG钾离子通道阻断剂。了解更多

Bulk Inquiry Free Sample
Quick View
Glyburide

Catalog No. A10433
Quick View

添加到收藏
K+ channel and CFTR Cl- channel blocker

Glyburide (Glibenclamide) 是一种抗糖尿病化合物，是一类磺脲类药物。了解更多

Bulk Inquiry Free Sample
Quick View
Gap 27

Catalog No. A14866
Quick View

添加到收藏
Gap junction blocker

Gap 27是衍生自连接蛋白43的肽，其是选择性的间隙连接阻断剂。了解更多

Bulk Inquiry Free Sample
Quick View
Amiloride HCl

Catalog No. A10064
Quick View

添加到收藏
Na+ channel blocker

Amiloride HCl是一种Na+通道阻滞剂，还抑制TRPP3通道和Na+/H+交换剂（NHE）。了解更多

Product Citations (2)

Bulk Inquiry
- Yu Y, .et al. Expression, Localization and Functional Activity of the Major Na+/H+ Exchange Isoforms Expressed in the Intestinal Cell Line Caco-2BBe, Cell Physiol Biochem, 2019, 52(5):1017-1038 PMID: 30977986
- Thomas D. Williams, .et al. The physiological regulation of macropinocytosis during Dictyostelium growth and development, J Cell Sci, 2018, Mar 15; 131(6): jcs213736 PMID: 29440238
Quick View
Azilsartan (TAK-536)

Catalog No. A11775
Quick View

添加到收藏
AT1 Receptor Blocker

Azilsartan (TAK-536)是一种用于治疗高血压的血管紧张素II受体拮抗剂。了解更多

Bulk Inquiry Free Sample
Quick View
PAP-1 (5-(4-Phenoxybutoxy)psoralen)

Catalog No. A11521
Quick View

添加到收藏
Kv1.3 blocker

PAP-1 (5-(4-Phenoxybutoxy)psoralen) 是一种有效的，选择性的，口服活性的?Kv1.3?阻滞剂 (EC50=2 nM)。PAP-1 以使用依赖性方式阻止 Kv1.3，并通过优先绑定到通道的 C 型灭活状态来起作用。了解更多

Product Citations (1)

Bulk Inquiry Free Sample
- Samuel Drinkall, .et al. The two pore potassium channel THIK-1 regulates NLRP3 inflammasome activation, Glia, 2022, Jul;70(7):1301-1316 PMID: 35353387
Quick View
TCS 5861528

Catalog No. A14126
Quick View

添加到收藏
TRPA1 channel blocker

TCS 5861528是TRPA1通道阻滞剂和AITC和4-HNE诱发的钙流入的拮抗剂。了解更多

Bulk Inquiry Free Sample
Quick View
Cilnidipine

Catalog No. A10215
Quick View

添加到收藏
Calcium channel blocker

Cilnidipine是提供血管平滑肌中L型电压门控钙通道和交感神经末梢N型钙通道的双重阻滞剂。了解更多

Bulk Inquiry Free Sample
Quick View
Clevidipine

Catalog No. A11746
Quick View

添加到收藏
Calcium channel blocker

Clevidipine是一种二氢吡啶类钙通道阻滞剂，用于在口服治疗不可行或不理想时降低血压。了解更多

Bulk Inquiry Free Sample
Quick View
Nifedipine

Catalog No. A10643
Quick View

添加到收藏
L-type calcium channel blocker.

Nifedipine是一种L型钙通道阻滞剂。了解更多

Bulk Inquiry Free Sample
Quick View
NP118809

Catalog No. A15192
Quick View

添加到收藏
N-type calcium channel blocker

NP118809是有效的N型钙通道阻滞剂（IC50 = 0.11 uM）；对L型钙通道的选择性好。了解更多

Bulk Inquiry
Quick View
Amlodipine

Catalog No. A10068
Quick View

添加到收藏
L-type calcium channel blocker

Amlodipine是一种L型钙通道阻滞剂，具有降压作用。它抑制去极化大鼠主动脉中Ca2 +诱导的收缩（IC50 = 1.9 nM），并在心血管疾病中显示出血管保护作用。了解更多

Bulk Inquiry Free Sample
Quick View
TAK-438 (vonoprazan)

Catalog No. A11239
Quick View

添加到收藏
potassium-competitive acid Blocker

TAK-438 (vonoprazan)是一种新型的钾竞争酸阻滞剂。了解更多

Bulk Inquiry Free Sample

联系我们

Not your Region? View all Distributors

溶液配制计算器

分子量计算器

稀释计算器

摩尔浓度计算器

ADOOQ 产品质量保证

Guaranteed product quality, 365 days Unconditional Return & Replacement

We promise all products to perform as described.