购物车 0 ￥ 0.00
微信关注
申请试用装

PROTAC Degrader

23 个项目

每页

设置降序顺序
  1. PROTAC CRBN Degrader-1
    Quick View

    PROTAC CRBN Degrader-1

    Catalog No. A18863
    Quick View
    CRBN degrader
    PROTAC CRBN Degrader-1 comprises a cereblon (CRBN) ligand binding group, a linker and an von Hippel-Landau (VHL) binding group. PROTAC CRBN Degrader-1 is an cereblon (CRBN) degrader. 了解更多
  2. PROTAC ERRα Degrader-2
    Quick View

    PROTAC ERRα Degrader-2

    Catalog No. A18904
    Quick View
    ERRa degrader
    PROTAC ERRalpha Degrader-2 comprises a MDM2 ligand binding group, a linker and an estrogen-related receptor alpha (ERRa) binding group. PROTAC ERRalpha Degrader-2 is an estrogen-related receptor alpha (ERRa) degrader. 了解更多
  3. PROTAC ERRα Degrader-1
    Quick View

    PROTAC ERRα Degrader-1

    Catalog No. A18910
    Quick View
    ERRα Degrader
    PROTAC ERRα Degrader-1 comprises a MDM2 ligand binding group, a linker and an estrogen-related receptor alpha (ERRa) binding group. PROTAC ERRα Degrader-1 is an estrogen-related receptor alpha (ERRa) degrader. 了解更多
  4. FKBP12 PROTAC dTAG-7
    Quick View

    FKBP12 PROTAC dTAG-7

    Catalog No. A19081
    Quick View
    heterobifunctional degrader
    FKBP12 PROTAC dTAG-7 (dTAG-7) is a heterobifunctional degrader. 了解更多
  5. THAL-SNS-032
    Quick View

    THAL-SNS-032

    Catalog No. A19088
    Quick View
    CDK9 degrader PROTAC
    THAL-SNS-032 is a selective CDK9 degrader PROTAC consisting of a CDK-binding SNS-032 ligand linked to a thalidomide derivative that binds the E3 ubiquitin ligase Cereblon (CRBN). 了解更多
  6. PROTAC FLT-3 degrader 1
    Quick View

    PROTAC FLT-3 degrader 1

    Catalog No. A18682
    Quick View
    FLT-3 ITD degrader
    PROTAC FLT-3 degrader 1 is an FLT-3 internal tandem duplication (ITD) degrader with an IC50 0.6 nM. Anti-proliferative activity; apoptosis induction. 了解更多
  7. PROTAC ER Degrader-3
    Quick View

    PROTAC ER Degrader-3

    Catalog No. A18519
    Quick View
    PROTAC ER Degrader-3 is an intermediate for synthesis of PAC. PAC, consists the ADCs linker and PROTACs, conjugated to an antibody. PAC extracts from patent WO2017201449A1, compound LP2. PAC conjugated to an antibody is a more marked estrogen receptor-alpha (ERα) degrader compared to PROTAC (without Ab). 了解更多
  8. ARV-771
    Quick View

    ARV-771

    Catalog No. A13255
    Quick View
    BET degrader
    ARV-771 is a potent BET degrader based on PROTAC technology with Kds of 34, 4.7, 8.3, 7.6, 9.6, and 7.6 nM for BRD2(1), BRD2(2), BRD3(1), BRD3(2), BRD4(1), and BRD4(2), respectively. 了解更多
  9. ZXH-3-26
    Quick View

    ZXH-3-26

    Catalog No. A18399
    Quick View
    PROTAC BRD4 degrader
    ZXH-3-26 is a selective PROTAC BRD4 degrader with a DC50/5h (DC50/5h referring to half-maximal degradation after 5 hours of treatment) of ~ 5 nM. 了解更多
  10. ERD-308
    Quick View

    ERD-308

    Catalog No. A18446
    Quick View
    ER PROTAC degrader
    ERD-308 is a highly potent PROTAC degrader of estrogen receptor (ER) for ER positive breast cancer treatment. 了解更多
  11. MT-802
    Quick View

    MT-802

    Catalog No. A18589
    Quick View
    BTK degrader
    MT-802 is a potent BTK degrader based on PROTAC technology, with a DC50 of 1 nM. MT-802 has potential to treat C481S mutant chronic lymphocytic leukemia (CLL). 了解更多
  12. VZ185
    Quick View

    VZ185

    Catalog No. A18685
    Quick View
    dual BRD7/9 PROTAC degrader
    VZ185 is a potent, fast, and selective dual BRD7/9 PROTAC degrader with DC50s of 4.5 and 1.8 nM, respectively. 了解更多
  13. MD-224
    Quick View
    • 最新产品

    MD-224

    Catalog No. A18712
    Quick View
    MDM2 degrader
    MD-224 is a first-in-class and highly potent small-molecule human murine double minute 2 (MDM2) degrader based on the proteolysistargeting chimera (PROTAC) concept. MD-224 has the potential to be a new class of anticancer agent. 了解更多
  14. PROTAC Bcl2 degrader-1
    Quick View

    PROTAC Bcl2 degrader-1

    Catalog No. A18355
    Quick View
    degrader
    PROTAC Bcl2 degrader-1 (Compound C5) is a PROTAC, which potently and selectively induces the degradation of Bcl-2 (IC50, 4.94 μM; DC50, 3.0 μM) and Mcl-1 (IC50, 11.81 μM) by introducing the E3 ligase cereblon (CRBN)-binding ligand pomalidomide to Mcl-1/Bcl-2 dual inhibitor Nap-1. 了解更多
  15. dMCL1-2
    Quick View

    dMCL1-2

    Catalog No. A18378
    Quick View
    MCL-1/PROTAC degrader
    dMCL1-2 is a potent and selective degrader of myeloid cell leukemia 1 (MCL1) based on PROTAC, which binds to MCL1 with a KD of 30 nM. dMCL1-2 activats the cellular apoptosis machinery by degradation of MCL1. 了解更多
  16. BETd-260
    Quick View

    BETd-260

    Catalog No. A12563
    Quick View
    BET degrader
    BETd-260 is a potent BET degrader based on PROTAC technology, with as low as 30 pM against BRD4 protein in RS4;11 leukemia cell line. 了解更多
  17. PROTAC Sirt2 Degrader-1
    Quick View

    PROTAC Sirt2 Degrader-1

    Catalog No. A20005
    Quick View
    Sirt2 degrader
    PROTAC Sirt2 Degrader-1 is a SirReal-based PROTAC, acts as a Sirt2 degrader, composed of a highly potent and isotype-selective Sirt2 inhibitor, a linker, and a bona fide cereblon ligand for E3 ubiquitin ligase. 了解更多
  18. PROTAC BET degrader-2
    Quick View

    PROTAC BET degrader-2

    Catalog No. A18785
    Quick View
    PROTAC BET degrader
    PROTAC BET degrader-2 is a highly potent degrader of Bromodomain and Extra-Terminal (BET) proteins with an IC50 value of 9.6 nM in cell growth inhibition in the RS4;11 cells and capable of achieving tumor regression. 了解更多
  19. dBET57
    Quick View

    dBET57

    Catalog No. A19133
    Quick View
    BRD4BD1degrader
    dBET57 is a potent and selective degrader of BRD4BD1 based on the PROTAC technology. 了解更多
  20. MZP-55
    Quick View

    MZP-55

    Catalog No. A19415
    Quick View
    BRD3/4 degrader
    MZP-55 is a selective degrader of BRD3/4 based on PROTAC technology, with a Kd of 8 nM for Brd4BD2. 了解更多
  21. MZP-54
    Quick View

    MZP-54

    Catalog No. A19426
    Quick View
    BRD3/4 degrader
    MZP-54 is a selective degrader of BRD3/4 based on PROTAC technology, with a Kd of 4 nM for Brd4BD2. 了解更多
  22. MZ1
    Quick View
    • 最新产品

    MZ1

    Catalog No. A17014
    Quick View
    BRD4 protein degrader
    MZ1是BRD2和BRD3上BRD4可逆，持久和选择性去除的有效诱导剂。 了解更多
  23. dBET1
    Quick View

    dBET1

    Catalog No. A16858
    Quick View
    BRD4 protein degrader
    dBET1是基于PROTAC技术的有效BRD4蛋白降解剂，EC50为430 nM。 了解更多

23 个项目

每页

设置降序顺序
FILTER BY:

Filtering:

  1. 作用机制: Degrader (降解剂) 删除该内容
清除全部
联系我们
ChinaChina

Adooq 中国 (南京百鑫德诺生物科技有限公司)

免费电话: 400-025-6535

企业QQ: 400-025-6535

www.adooq.cn

sales@adooq.cn

United StatesUnited States

Adooq Bioscience

Toll Free: (866) 930-6790

Fax: +1-323-606-8156

Email: sales@adooq.com

Not your Region? View all Distributors

溶液配制计算器

分子量计算器

稀释计算器

摩尔浓度计算器

ADOOQ 产品质量保证
Guaranteed product quality, 365 days Unconditional Return & Replacement

We promise all products to perform as described.

立即申请
Get Code
联系我们
查看FAQs

Adooq 公司

产品订购

技术资源

地址

© 2006-2019 AdooQ BioScience （南京百鑫德诺生物科技有限公司）. All Rights Reserved.
苏ICP备14027875号
Accept Payment
Rewards