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PROTAC ERRα Degrader-1 comprises a MDM2 ligand binding group, a linker and an estrogen-related receptor alpha (ERRa) binding group. PROTAC ERRα Degrader-1 is an estrogen-related receptor alpha (ERRa) degrader.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 9.02 mL | 45.09 mL | 90.18 mL |
| 0.5 mM | 1.8 mL | 9.02 mL | 18.04 mL |
| 1 mM | 0.9 mL | 4.51 mL | 9.02 mL |
| 5 mM | 0.18 mL | 0.9 mL | 1.8 mL |
*The above data is based on the productmolecular weight 1108.91. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A18910 |
|---|---|
| 作用机制 | Degrader (降解剂) |
| M. Wt | 1108.91 |
| Formula | C54H49Cl2F6N7O8 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 2306388-84-9 |
| Synonyms | 0 |
| SMILES | O=C(N1CC(N(CC(NCCNC(/C(C#N)=C/C2=CC(OC)=C(OCC3=C(C=C(C(F)(F)F)C=C3)C(F)(F)F)C=C2)=O)=O)CC1)=O)N4[C@@H](C5=CC=C(Cl)C=C5)[C@@H](C6=CC=C(Cl)C=C6)N=C4C7=C(C=C(OC)C=C7)OC(C)C |
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