Protein Tyrosine Phosphatase

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  1. DPM-1001

    Catalog No. A18674
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    PTP1B inhibitor
    DPM-1001 is a potent, specific, orally bioavailable and non-competitive inhibitor of protein-tyrosine phosphatase (PTP1B) with an IC50 of 100 nM, an an analog of the specific PTP1B inhibitor trodusquemine (MSI-1436; IC50=600 nM). DPM-1001 has anti-diabetic property. 了解更多
  2. PTP1B-IN-8

    Catalog No. A19109
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    PTP1B inhibitor
    PTP1B-IN-8 is a potent and selective potent protein tyrosine phosphatase-1B (PTP1B) inhibitor extracted from patent CN103626692A, example 1. 了解更多
  3. PTP1B-IN-3

    Catalog No. A21149
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    PTP1B inhibitor
    PTP1B-IN-3 is a potent and selective PTP1B inhibitor with IC50s of 120 nM (PTP1B) and 120 nM (TCPTP), respectively. 了解更多
  4. PTP1B-IN-1

    Catalog No. A22000
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    PTP1B inhibitor
    PTP1B-IN-1 is a potent protein tyrosine phosphatase-1B (PTP1B) inhibitor with IC50 of 1.6 mM; 1,2,5-thiadiazolidin-3-one-1,1-dioxide scaffold for derivatives synthesis. 了解更多
  5. TCS 401

    Catalog No. A21859
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    PTP1B inhibitor
    TCS 401 is a selective inhibitor of protein tyrosine phosphatase 1B (PTP1B). 了解更多
  6. SF1670

    Catalog No. A13475
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    PTEN 抑制剂
    SF1670是选择性PTEN抑制剂(IC50 = 2 uM)。由于PTEN-mTOR通路对于控制皮质脊髓神经元的再生能力至关重要,因此PTEN缺失或其抑制剂可增强成年皮质脊髓神经元的再生能力。在临床相关的小鼠模型中,用SF1670进行预处理可增强粒细胞输注的功效。 了解更多
  7. Shikonin

    Catalog No. A12125
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    PTEN 抑制剂
    Shikonin一种中草药成分,抑制趋化因子受体功能,抑制人类免疫缺陷病毒1型。 了解更多
  8. BVT 948

    Catalog No. A15383
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    PTP 抑制剂
    BVT 948是一种非竞争性PTP(蛋白酪氨酸磷酸酶)抑制剂。 了解更多
  9. TCS 401 free base

    Catalog No. A15390
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    PTP1B 抑制剂
    TCS 401是蛋白酪氨酸磷酸酶1B(PTP1B)的选择性抑制剂(对于PTP1B,CD45 D1D2,PTPβ,PTPεD1,SHP-1,Ki值为0.29、59、560、1100,> 2000,> 2000和> 2000μM,分别为PTPαD1和LAR D1D2)。 了解更多

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