PRT 4165

Name: PRT 4165
SKU: A15453

目录号: A15453

Bmi1/Ring1A 抑制剂

PRT 4165 Chemical Structure

CAS NO. 31083-55-3

PRT 4165是Bmi1/Ring1A抑制剂，Bmi1/Ring1A是多梳抑制复合物1（PRC1）的亚基。它可以防止Bmi1/Ring1A介导的泛素化和拓扑异构酶2alpha的药物诱导降解。

库存：现货

规格	价格	数量
10 mg	￥ 385.00
25 mg	￥ 770.00
50 mg	￥ 1,134.00

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生物活性

PRT 4165是Bmi1/Ring1A抑制剂，Bmi1/Ring1A是多梳抑制复合物1（PRC1）的亚基。它可以防止Bmi1/Ring1A介导的泛素化和拓扑异构酶2alpha的药物诱导降解。

溶解度 *

In vitro	DMSO	10 mg/mL (42.51 mM)
	Water	Insoluble
	Ethanol	3 mg/mL (12.75 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	42.51 mL	212.55 mL	425.1 mL
0.5 mM	8.5 mL	42.51 mL	85.02 mL
1 mM	4.25 mL	21.25 mL	42.51 mL
5 mM	0.85 mL	4.25 mL	8.5 mL

*The above data is based on the productmolecular weight 235.24. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A15453
作用机制	Inhibitor (抑制剂)
M. Wt	235.24
Formula	C15H9NO2
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	31083-55-3
Synonyms	PRT4165, PRT-4165
SMILES	O=C(C1=CC=CC=C1C/2=O)C2=C\C3=CC=CN=C3