Purinergic (P2Y) Receptors
-
P2Y1 拮抗剂
BPTU是P2Y1拮抗剂。已经显示出它具有抗血栓形成的功效并减少了出血的可能性。
了解更多
-
P2Y12 receptors inhibitor
Cangrelor Tetrasodium is a high-affinity, reversible inhibitor of P2Y12 receptors that causes almost complete inhibition of ADP-induced platelet aggregate. It is a modified ATP derivative stable to enzymatic degradation. Unlike clopidogrel (Plavix), which is a prodrug, cangrelor is an active drug not requiring metabolic conversion.
了解更多
-
P2Y12 platelet inhibitor
Vicagrel, an acetate derivative of Clopidogrel, is a P2Y12 platelet inhibitor potentially for the treatment of thrombosis.
了解更多
-
P2Y12 receptor inhibitor
Clopidogrel thiolactone is a P2Y12 receptor inhibitor, is a potent antiplatelet agent.
了解更多
-
platelet P2Y12 antagonist
Elinogrel (PRT060128) is a potent, direct acting, competitive, and reversible platelet P2Y12 antagonist (IC50=20 nM). It is orally and intravenously available and has potent antiplatelet effects.
了解更多
-
platelet inhibitor
Prasugrel (Effient)是一种新型的血小板抑制剂,用于减少急性冠脉综合征(PCI)患者的血栓性心血管事件(包括支架血栓形成)。
了解更多
-
(+)-Clopidogrel hydrogen sulfate (Plavix)是一种口服的,噻吩吡啶类抗血小板药物。
了解更多
-
P2Y12 拮抗剂
Ticagrelor (AZD6140)是第一个可逆结合的口服P2Y(12)受体拮抗剂,可阻断ADP诱导的血小板聚集。
了解更多
-
P2Y6 Receptor 拮抗剂
MRS 2578是P2Y6核苷酸受体的选择性拮抗剂。
了解更多
-
P2Y12 receptor 拮抗剂
AZD1283是P2Y12受体的有效拮抗剂,EC50为3.0 ug/kg/min,TI> 10;结合IC50为11 nM。
了解更多
-
Methylthioadenosine是存在于所有哺乳动物组织中的天然存在的含硫核苷。
了解更多
-
P2Y12 拮抗剂
Prasugrel Hydrochloride是噻吩并吡啶ADP受体(P2Y12)拮抗剂,用于减少血栓性心血管事件。
了解更多
-
platelet inhibitor
Clopidogrel is a well-known and orally active platelet inhibitor that targets P2Y12 receptor. Clopidogrel is used to inhibit blood clots in coronary artery disease, peripheral vascular disease, and cerebrovascular disease.
了解更多