Purinergic (P2Y) Receptors
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platelet inhibitor
Prasugrel (Effient)是一种新型的血小板抑制剂,用于减少急性冠脉综合征(PCI)患者的血栓性心血管事件(包括支架血栓形成)。
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platelet inhibitor
Clopidogrel is a well-known and orally active platelet inhibitor that targets P2Y12 receptor. Clopidogrel is used to inhibit blood clots in coronary artery disease, peripheral vascular disease, and cerebrovascular disease.
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P2Y12 receptors inhibitor
Cangrelor Tetrasodium is a high-affinity, reversible inhibitor of P2Y12 receptors that causes almost complete inhibition of ADP-induced platelet aggregate. It is a modified ATP derivative stable to enzymatic degradation. Unlike clopidogrel (Plavix), which is a prodrug, cangrelor is an active drug not requiring metabolic conversion.
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P2Y12 platelet inhibitor
Vicagrel, an acetate derivative of Clopidogrel, is a P2Y12 platelet inhibitor potentially for the treatment of thrombosis.
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P2Y12 receptor inhibitor
Clopidogrel thiolactone is a P2Y12 receptor inhibitor, is a potent antiplatelet agent.
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