产品详情

R-10015, a broad-spectrum antiviral compound for HIV infection, acts as a potent and selective inhibitor of LIM domain kinase (LIMK) and binds to the ATP-binding pocket, with an IC50 of 38 nM for human LIMK1.

溶解度 *

In vitro	DMSO	76 mg/mL (184.98 mM)
	Water	<1 mg/mL
	Ethanol	9 mg/mL (21.9 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.34 mL	121.7 mL	243.39 mL
0.5 mM	4.87 mL	24.34 mL	48.68 mL
1 mM	2.43 mL	12.17 mL	24.34 mL
5 mM	0.49 mL	2.43 mL	4.87 mL

*The above data is based on the productmolecular weight 410.86. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A18806
作用机制	Inhibitor (抑制剂)
M. Wt	410.86
Formula	C20H19ClN6O2
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	2097938-51-5
Synonyms	R10015, R 10015
SMILES	O=C(C1=CC=C2NC(C3CCN(C4=C5C(NC=C5Cl)=NC=N4)CC3)=NC2=C1)OC