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Ras-IN-3144 is a pan-RAS inhibitor which inhibits RAS signaling pathways in cancer cells and prevents the growth of RAS mutant mouse cancer xenografts.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 13.96 mL | 69.81 mL | 139.61 mL |
| 0.5 mM | 2.79 mL | 13.96 mL | 27.92 mL |
| 1 mM | 1.4 mL | 6.98 mL | 13.96 mL |
| 5 mM | 0.28 mL | 1.4 mL | 2.79 mL |
*The above data is based on the productmolecular weight 716.262. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A17222 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 716.262 |
| Formula | C36H41Cl2F3N6O2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1835283-94-7 |
| Synonyms | RasIN3144, Ras IN-3144; Ras-IN 3144; Ras-IN-3144; 3144; pan-RAS inhibitor-3144 |
| SMILES | O=C(C1(N)CCNCC1)NCCCN2C=C(C3=CC=C(OC(F)(F)F)C=C3)C4=C2C=CC(CN5CCN(CC6=C(Cl)C=CC=C6Cl)CC5)=C4 |
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