RepSox (SJN 2511)

Name: RepSox (SJN 2511)
SKU: A11762

目录号: A11762

Product Citations (2)

RepSox (SJN 2511) Chemical Structure

CAS NO. 446859-33-2

RepSox (SJN 2511)是TGF-βI型受体ALK5的选择性抑制剂（ALK5自磷酸化和ALK5结合的IC50值分别为0.004和0.023μM）。

库存：现货

规格	价格	数量
10 mg	￥ 630.00
25 mg	￥ 1,400.00
50 mg	￥ 2,170.00
100 mg	￥ 3,640.00
10mM * 1mL in DMSO	￥ 455.00

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生物活性

RepSox (SJN 2511)是TGF-βI型受体ALK5的选择性抑制剂（ALK5自磷酸化和ALK5结合的IC50值分别为0.004和0.023μM）。

靶点信息

TGFβR1(ALK5) (Cell-free assay)
4 nM

溶解度 *

In vitro	DMSO	49 mg/mL (170.54 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	34.8 mL	174.02 mL	348.04 mL
0.5 mM	6.96 mL	34.8 mL	69.61 mL
1 mM	3.48 mL	17.4 mL	34.8 mL
5 mM	0.7 mL	3.48 mL	6.96 mL

*The above data is based on the productmolecular weight 287.32. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A11762
M. Wt	287.32
Formula	C17H13N5
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	446859-33-2
Synonyms	E-616452, SJN 2511, ALK 5 inhibitor
SMILES	CC1=CC=CC(=N1)C2=C(C=NN2)C3=NC4=C(C=C3)N=CC=C4