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Retigabine dihydrochloride是具有抗惊厥活性的Kv7.2-7.5（KCNQ2-5）神经元钾通道开放剂。
| In vitro | DMSO | 65 mg/mL (172.75 mM) | |
| Water | 65 mg/mL (172.75 mM) | ||
| Ethanol | 22 mg/mL | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.58 mL | 132.89 mL | 265.78 mL |
| 0.5 mM | 5.32 mL | 26.58 mL | 53.16 mL |
| 1 mM | 2.66 mL | 13.29 mL | 26.58 mL |
| 5 mM | 0.53 mL | 2.66 mL | 5.32 mL |
*The above data is based on the productmolecular weight 376.25. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A15222 |
|---|---|
| M. Wt | 376.25 |
| Formula | C16H20Cl2FN3O2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 150812-13-8 |
| Synonyms | D 20443 dihydrochloride, D-20443 dihydrochloride, D20443 dihydrochloride |
| SMILES | CCOC(=O)NC1=C(C=C(C=C1)NCC2=CC=C(C=C2)F)N.Cl.Cl |
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