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Retigabine是一种新型的抗痉挛剂,在大范围的惊厥模型具有活性。其发挥活性的机制主要是开放神经元的KCNQ2-5电压门控钾离子通道。
In vitro | DMSO | 58 mg/mL (191.21 mM) | |
Water | Insoluble | ||
Ethanol | 34 mg/mL (112.08 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 32.97 mL | 164.83 mL | 329.66 mL |
0.5 mM | 6.59 mL | 32.97 mL | 65.93 mL |
1 mM | 3.3 mL | 16.48 mL | 32.97 mL |
5 mM | 0.66 mL | 3.3 mL | 6.59 mL |
*The above data is based on the productmolecular weight 303.34. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A11922 |
---|---|
M. Wt | 303.34 |
Formula | C16H18FN3O2 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 150812-12-7 |
SMILES | CCOC(=O)NC1=C(C=C(C=C1)NCC2=CC=C(C=C2)F)N |
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