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RG7713 (RO5028442) is a highly potent and selective Brain-Penetrant Vasopressin 1a (V1a) receptor antagonist with Kis of 1 nM (hV1a) and 39 nM (mV1a).
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.83 mL | 114.17 mL | 228.33 mL |
| 0.5 mM | 4.57 mL | 22.83 mL | 45.67 mL |
| 1 mM | 2.28 mL | 11.42 mL | 22.83 mL |
| 5 mM | 0.46 mL | 2.28 mL | 4.57 mL |
*The above data is based on the productmolecular weight 437.96. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A21380 |
|---|---|
| 作用机制 | Antagonist (拮抗剂) |
| M. Wt | 437.96 |
| Formula | C25H28ClN3O2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 920022-47-5 |
| Synonyms | RO5028442,RO 5028442, RO-5028442, RG 7713, RG-7713 |
| SMILES | O=C(C1=CN(CCN(C)C)C2=C1C=CC(Cl)=C2)N3CCC4(C(C=CC=C5)=C5CO4)CC3 |
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