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Ribociclib hydrochloride (LEE011 hydrochloride) is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively,
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.23 mL | 106.16 mL | 212.31 mL |
| 0.5 mM | 4.25 mL | 21.23 mL | 42.46 mL |
| 1 mM | 2.12 mL | 10.62 mL | 21.23 mL |
| 5 mM | 0.42 mL | 2.12 mL | 4.25 mL |
*The above data is based on the productmolecular weight 471. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A22303 |
|---|---|
| M. Wt | 471 |
| Formula | C23H31ClN8O |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 2 years |
| CAS No. | 1211443-80-9 |
| Synonyms | LEE011 hydrochloride |
| SMILES | O=C(N(C)C)C(N1C2CCCC2)=CC(C1=N3)=CN=C3NC(N=C4)=CC=C4N5CCNCC5.Cl |
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