RIP Kinase
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RIPK1-IN-4
Catalog No. A21029 RIP1 kinase inhibitorRIPK1-IN-4 (compound 8) is a potent and selective type II kinase inhibitor of receptor interacting protein 1 (RIP1) kinase and binds to a DLG-out inactive form of RIP1 with an IC50s of 16 nM and 10 nM for RIP1 and ADP-Glo kinase. 了解更多 -
RIPK1-IN-7
Catalog No. A18940 RIPK1 inhibitorRIPK1-IN-7 is a potent and selective RIPK1 inhibitor with a Kd of 4 nM and an enzymatic IC50 of 11 nM. RIPK1-IN-7 exhibits excellent antimetastasis activity in the experimental B16 melanoma lung metastasis model. 了解更多 -
RIPK1-IN-3
Catalog No. A19023 RIPK1 inhibitorRIPK1-IN-3 (Example 38), a RIPK1 inhibitor, extracted from patent WO2018148626A1, possesses anti-inflammatory proprieties. 了解更多 -
GSK2982772
Catalog No. A19380 RIP1 kinase inhibitorGSK2982772 is a potent, orally active and ATP competitive RIP1 kinase inhibitor with IC50 values of 16 nM and 20 nM for human and monkey RIP1, respectively. 了解更多 -
GSK3145095
Catalog No. A19427 RIP1 kinase inhibitorGSK3145095 is a RIP1 kinase inhibitor with an IC50 of 6.3 nM . 了解更多 -
RIP2 kinase inhibitor 2
Catalog No. A16313 RIP2 kinase 抑制剂RIP2 kinase inhibitor 2 是从专利WO/2014043437 A1(化合物实施例9)中提取的受体相互作用蛋白2(RIP2)激酶抑制剂。 了解更多 -
RIP2 kinase inhibitor 1
Catalog No. A16312 RIP2 kinase 抑制剂RIP2 kinase inhibitor 1 是从专利WO/2014043446 A1(化合物实施例1)中提取的受体相互作用蛋白2(RIP2)激酶抑制剂。 了解更多 -
Necrostatin-1
Catalog No. A11973 RIPK1 抑制剂Necrostatin-1是一种与ATP竞争的,与受体相互作用的蛋白激酶1(RIPK1)的变构抑制剂(EC50 = 182 nM)。 了解更多