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Ritanserin (R 55667) is a highly potent, relatively selective, orally active, long acting antagonist of 5-HT2 receptor, with an IC50 of 0.9 nM, less active on Histamine H1, Dopamine D2, Adrenergic α1, Adrenergic α2 receptors.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.94 mL | 104.7 mL | 209.39 mL |
| 0.5 mM | 4.19 mL | 20.94 mL | 41.88 mL |
| 1 mM | 2.09 mL | 10.47 mL | 20.94 mL |
| 5 mM | 0.42 mL | 2.09 mL | 4.19 mL |
*The above data is based on the productmolecular weight 477.57. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A21976 |
|---|---|
| 作用机制 | Antagonist (拮抗剂) |
| M. Wt | 477.57 |
| Formula | C27H25F2N3OS |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 87051-43-2 |
| Synonyms | R 55667, R55667, R-55667 |
| SMILES | CC1=C(C(N(C=CS2)C2=N1)=O)CCN(CC/3)CCC3=C(C4=CC=C(F)C=C4)\C5=CC=C(F)C=C5 |
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