Ro 3306

Name: Ro 3306
SKU: A14437

目录号: A14437

CDK1 抑制剂

Product Citations (2)

Ro 3306 Chemical Structure

CAS NO. 872573-93-8

Ro 3306是一种具有ATP竞争能力的有效细胞周期蛋白依赖性激酶（cdk）1抑制剂（cdk1/cyclin B1和cdk1/cyclin A的Ki值分别为35和110 nM。

库存：现货

规格	价格	数量
10 mg	￥ 700.00
25 mg	￥ 1,260.00
50 mg	￥ 2,100.00

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生物活性

Ro 3306是一种具有ATP竞争能力的有效细胞周期蛋白依赖性激酶（cdk）1抑制剂（cdk1/cyclin B1和cdk1/cyclin A的Ki值分别为35和110 nM。

Targets

Target	Value
CDK1	ki: 20nM
PKCδ	ki: 318nM
SGK	ki: 497nM
ERK	ki: 1980nM
PKA	ki: >2000nM
Akt	ki: >2000nM
PKCα	ki: >2000nM
Fyn	ki: >2000nM
EphB3	ki: >2000nM

溶解度 *

In vitro	DMSO	Warmed: 12 mg/mL (34.14 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	28.45 mL	142.27 mL	284.54 mL
0.5 mM	5.69 mL	28.45 mL	56.91 mL
1 mM	2.85 mL	14.23 mL	28.45 mL
5 mM	0.57 mL	2.85 mL	5.69 mL

*The above data is based on the productmolecular weight 351.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A14437
作用机制	Inhibitor (抑制剂)
M. Wt	351.45
Formula	C18H13N3OS2
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	872573-93-8
Synonyms	Ro3306, Ro-3306
SMILES	C1=CC2=C(C=CC(=C2)/C=C/3\C(=O)N=C(S3)NCC4=CC=CS4)N=C1