产品详情
Rotundine (L-tetrahydropalmatine, L-THP)是一种选择性的多巴胺D1受体拮抗剂,IC50为166 nM。
靶点信息
D1 receptor | 5-HT1A | D2 receptor | D3 receptor | |
166 nM | 347 nM | 1.47 μM | 3.25 μM |
In vitro | DMSO | 8 mg/mL (22.5 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 28.13 mL | 140.67 mL | 281.35 mL |
0.5 mM | 5.63 mL | 28.13 mL | 56.27 mL |
1 mM | 2.81 mL | 14.07 mL | 28.13 mL |
5 mM | 0.56 mL | 2.81 mL | 5.63 mL |
*The above data is based on the productmolecular weight 355.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A11998 |
---|---|
M. Wt | 355.43 |
Formula | C21H25NO4 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 483-14-7 |
SMILES | COC1=C(C2=C(C[C@H]3C4=CC(=C(C=C4CCN3C2)OC)OC)C=C1)OC |
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