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Rp-8-Br-PET-cGMPS是cGKI（Ki = 30 nM）和cGKII（cGMP依赖性蛋白激酶G）的代谢稳定，竞争性抑制剂，可阻断cGMP门控的视网膜类型离子通道（IC50 = 25 ?M）。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.79 mL | 88.93 mL | 177.85 mL |
| 0.5 mM | 3.56 mL | 17.79 mL | 35.57 mL |
| 1 mM | 1.78 mL | 8.89 mL | 17.79 mL |
| 5 mM | 0.36 mL | 1.78 mL | 3.56 mL |
*The above data is based on the productmolecular weight 562.27. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A16030 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 562.27 |
| Formula | C18H14BrN5NaO6PS |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 185246-32-6 |
| SMILES | C1C2C(C(C(O2)N3C4=C(C(=O)N5C=C(NC5=N4)C6=CC=CC=C6)N=C3Br)O)OP(=O)(O1)[S-].[Na+] |
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