RSL3

Name: RSL3
SKU: A15865

目录号: A15865

Ferroptosis inhibitor

Product Citations (3)

RSL3 Chemical Structure

CAS NO. 1219810-16-8

RSL3 is a ferroptosis activator in a VDAC-independent manner,exhibiting selectivity for tumor cells bearing oncogenic RAS.

库存：现货

规格	价格	数量
5 mg	￥ 567.00
10 mg	￥ 966.00
25 mg	￥ 1,701.00

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产品详情

生物活性

RSL3 is a ferroptosis activator in a VDAC-independent manner,exhibiting selectivity for tumor cells bearing oncogenic RAS.

靶点信息

Gpx4

溶解度 *

In vitro (25°C)	DMSO	82 mg/mL (185.99 mM)
	Water	Insoluble
	Ethanol	20 mg/mL
In vivo	2% DMSO+30% PEG 300+2% Tween 80+ddH2O	1 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.68 mL	113.41 mL	226.82 mL
0.5 mM	4.54 mL	22.68 mL	45.36 mL
1 mM	2.27 mL	11.34 mL	22.68 mL
5 mM	0.45 mL	2.27 mL	4.54 mL

*The above data is based on the productmolecular weight 440.88. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A15865
作用机制	Inhibitor (抑制剂)
M. Wt	440.88
Formula	C23H21ClN2O5
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1219810-16-8
Synonyms	1S,3R-RSL3
SMILES	COC(C1=CC=C([C@@]2([H])C3=C(C4=CC=CC=C4N3)C[C@](N2C(CCl)=O)([H])C(OC)=O)C=C1)=O