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Ruxolitinib sulfate

Ruxolitinib sulfate

Name: Ruxolitinib sulfate
SKU: A11467

目录号: A11467

JAK1/2 inhibitor

Ruxolitinib sulfate Chemical Structure

CAS NO. 1092939-16-6

Ruxolitinib sulfate (INCB018424 sulfate) is the first potent, selective JAK1/2 inhibitor to enter the clinic with IC50s of 3.3 nM/2.8 nM, and has > 130-fold selectivity for JAK1/2 versus JAK3.

库存：现货

规格	价格	数量
5 mg	￥ 378.00
10 mg	￥ 651.00
50 mg	￥ 1,932.00
100 mg	￥ 3,864.00

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生物活性

Ruxolitinib sulfate (INCB018424 sulfate) is the first potent, selective JAK1/2 inhibitor to enter the clinic with IC50s of 3.3 nM/2.8 nM, and has > 130-fold selectivity for JAK1/2 versus JAK3.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.73 mL	123.63 mL	247.26 mL
0.5 mM	4.95 mL	24.73 mL	49.45 mL
1 mM	2.47 mL	12.36 mL	24.73 mL
5 mM	0.49 mL	2.47 mL	4.95 mL

*The above data is based on the productmolecular weight 404.44. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A11467
作用机制	Inhibitor (抑制剂)
M. Wt	404.44
Formula	C17H20N6O4S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1092939-16-6
Synonyms	INCB018424 sulfate, INCB 018424, INCB-018424
SMILES	[H][C@@](C1CCCC1)(N2N=CC(C3=C4C=CNC4=NC=N3)=C2)CC#N.O=S(O)(O)=O