S1P Receptor
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Fingolimod
Catalog No. A17798 S1P antagonistFingolimod is a sphingosine 1-phosphate (S1P) antagonist with IC50 of 0.033 nM in K562 and NK cells. Fingolimod also is a pak1 activator, a immunosuppressant. 了解更多 -
KRP-203
Catalog No. A13308 -
Ponesimod
Catalog No. A13307 -
NS13001
Catalog No. A15833 -
RPC1063 (Ozanimod)
Catalog No. A15819 -
PF-543 Citrate
Catalog No. A15210 SphK1 抑制剂PF-543 Citrate是一种新型的SphK1细胞渗透抑制剂,K(i)为3.6 nM,PF-543具有鞘氨醇竞争性,对SphK1的选择性是SphK2同种型的100倍以上。 了解更多 -
CYM 5442 HCl
Catalog No. A13637 -
PF-543
Catalog No. A13039 -
BAF312 (Siponimod)
Catalog No. A12906 -
FTY720 (Fingolimod)
Catalog No. A10408 S1P Receptor 拮抗剂FTY720 (Fingolimod)是ISP-1(肉豆蔻酸)的衍生物,ISP-1是中国草药Iscaria sinclarii的真菌代谢物,也是鞘氨醇的结构类似物。 了解更多 -
PF429242 dihydrochloride
Catalog No. A21386 S1P inhibitorPF429242 dihydrochloride is a reversible and competitive S1P inhibitor with an IC50 of 175 nM. 了解更多 -
FTY720 (S)-Phosphate
Catalog No. A21324 S1PR1 agonistFTY720 (S)-Phosphate is an agonist of S1P receptor 1 (S1PR1), used in the research of acute inflammatory diseases such as acute lung injury. 了解更多 -
VPC 23019
Catalog No. A20102 S1P antagonistVPC 23019, an aryl amide-containing Sphingosine 1-phosphate (S1P) analog, is a competitive antagonist at the S1P1 and S1P3 receptors (pKi= 7.86 and 5.93, respectively) and an agonist at the S1P4 and S1P5 receptors (pEC50= 6.58 and 7.07, respectively). 了解更多 -
K145 hydrochloride
Catalog No. A16289 -
K145
Catalog No. A16288