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Safinamide是一种高度选择性和可逆的B型单胺氧化酶（MAO-B）抑制剂，可增加新纹状体多巴胺的浓度。
| In vitro | DMSO | 52 mg/mL (171.99 mM) | |
| Ethanol | <1 mg/mL | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 33.08 mL | 165.38 mL | 330.75 mL |
| 0.5 mM | 6.62 mL | 33.08 mL | 66.15 mL |
| 1 mM | 3.31 mL | 16.54 mL | 33.08 mL |
| 5 mM | 0.66 mL | 3.31 mL | 6.62 mL |
*The above data is based on the productmolecular weight 302.34. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A13294 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 302.34 |
| Formula | C17H19FN2O2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 133865-89-1 |
| Synonyms | EMD 1195686, FCE 26743 |
| SMILES | C[C@@H](C(=O)N)NCC1=CC=C(C=C1)OCC2=CC(=CC=C2)F |
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