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Salirasib是Prenylated蛋白甲基转移酶（PPMTase）的抑制剂，Ki值为2.6 uM。
靶点信息
| PPMTase | ||||
| 2.6 μM(Ki) |
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 27.89 mL | 139.45 mL | 278.91 mL |
| 0.5 mM | 5.58 mL | 27.89 mL | 55.78 mL |
| 1 mM | 2.79 mL | 13.95 mL | 27.89 mL |
| 5 mM | 0.56 mL | 2.79 mL | 5.58 mL |
*The above data is based on the productmolecular weight 358.54. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A11572 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 358.54 |
| Formula | C22H30O2S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 162520-00-5 |
| Synonyms | S-Farnesylthiosalicylic acid, Farnesyl Thiosalicylic Acid, FTS |
| SMILES | CC(=CCCC(=CCCC(=CCSC1=CC=CC=C1C(=O)O)C)C)C |
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