SANT-1

Name: SANT-1
SKU: A13095

目录号: A13095

Sonic hedgehog 抑制剂

SANT-1 Chemical Structure

CAS NO. 304909-07-7

SANT-1是有效的细胞渗透性Sonic刺猬（Shh）信号传导抑制剂；平滑活性的高亲和力拮抗剂（KD = 1.2 nM）。以20 nM的IC50抑制平滑的激动剂作用（在Shh-LIGHT2细胞中）。

库存：现货

规格	价格	数量
10 mg	￥ 567.00
25 mg	￥ 1,134.00
50 mg	￥ 1,701.00
100 mg	￥ 2,835.00
10mM * 1mL in DMSO	￥ 672.00

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产品详情

生物活性

靶点信息

Smoothened receptor
1.2 nM(Kd)

溶解度 *

In vitro	DMSO	21 mg/mL (56.22 mM)
	Water	Insoluble
	Ethanol	20 mg/mL (53.54 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	26.77 mL	133.87 mL	267.74 mL
0.5 mM	5.35 mL	26.77 mL	53.55 mL
1 mM	2.68 mL	13.39 mL	26.77 mL
5 mM	0.54 mL	2.68 mL	5.35 mL

*The above data is based on the productmolecular weight 373.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A13095
作用机制	Inhibitor (抑制剂)
M. Wt	373.5
Formula	C23H27N5
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	304909-07-7
Synonyms	SANT 1, SANT1
SMILES	CC1=C(C(=NN1C2=CC=CC=C2)C)/C=N/N3CCN(CC3)CC4=CC=CC=C4