产品详情
SCH 442416是一种选择性的腺苷A2A受体拮抗剂。以高亲和力结合人和大鼠A2A受体(Ki值分别为0.048和0.5 nM)。在体外对hA2A的选择性比hA1高> 23000倍,并且对hA2B和hA3受体的亲和力最小(IC50> 10μM)。
In vitro | DMSO | 72 mg/mL (184.89 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 25.68 mL | 128.4 mL | 256.79 mL |
0.5 mM | 5.14 mL | 25.68 mL | 51.36 mL |
1 mM | 2.57 mL | 12.84 mL | 25.68 mL |
5 mM | 0.51 mL | 2.57 mL | 5.14 mL |
*The above data is based on the productmolecular weight 389.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A12695 |
---|---|
作用机制 | Antagonist (拮抗剂) |
M. Wt | 389.42 |
Formula | C20H19N7O2 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 316173-57-6 |
Synonyms | SCH442416, SCH-442416 |
SMILES | COC1=CC=C(C=C1)CCCN2C3=C(C=N2)C4=NC(=NN4C(=N3)N)C5=CC=CO5 |
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