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SEL120-34A是一种有效且选择性的CDK8抑制剂，在AML细胞中具有高水平的STAT1和STAT5反式激活域丝氨酸磷酸化活性。
| In vitro | DMSO | 9 mg/mL (19.97 mM) | |
| Water | 77 mg/mL (170.88 mM) | ||
| Ethanol | Insoluble | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.15 mL | 120.73 mL | 241.46 mL |
| 0.5 mM | 4.83 mL | 24.15 mL | 48.29 mL |
| 1 mM | 2.41 mL | 12.07 mL | 24.15 mL |
| 5 mM | 0.48 mL | 2.41 mL | 4.83 mL |
*The above data is based on the productmolecular weight 414.145. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A17086 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 414.145 |
| Formula | C15H18Br2N4 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1609522-33-9 |
| Synonyms | SEL 120-34A, SEL-120-34A, SEL12034A, SEL 12034A, SEL-12034A |
| SMILES | CC1=C2C3=C(C(Br)=C1Br)CCCN3C(N4CCNCC4)=N2 |
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