SF1670

Name: SF1670
SKU: A13475

目录号: A13475

PTEN 抑制剂

SF1670 Chemical Structure

CAS NO. 345630-40-2

SF1670是选择性PTEN抑制剂（IC50 = 2 uM）。由于PTEN-mTOR通路对于控制皮质脊髓神经元的再生能力至关重要，因此PTEN缺失或其抑制剂可增强成年皮质脊髓神经元的再生能力。在临床相关的小鼠模型中，用SF1670进行预处理可增强粒细胞输注的功效。

库存：现货

规格	价格	数量
5 mg	￥ 756.00
10 mg	￥ 1,288.00
25 mg	￥ 2,268.00
50 mg	￥ 3,780.00
10mM * 1mL in DMSO	￥ 770.00

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产品详情

生物活性

靶点信息

PTEN
2 μM

溶解度 *

In vitro	DMSO	Warmed: 27 mg/mL (87.84 mM)
	Water	Insoluble
	Ethanol	Warmed: 1 mg/mL (3.25 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	32.53 mL	162.65 mL	325.31 mL
0.5 mM	6.51 mL	32.53 mL	65.06 mL
1 mM	3.25 mL	16.27 mL	32.53 mL
5 mM	0.65 mL	3.25 mL	6.51 mL

*The above data is based on the productmolecular weight 307.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A13475
作用机制	Inhibitor (抑制剂)
M. Wt	307.4
Formula	C19H17NO3
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	345630-40-2
Synonyms	SF 1670, SF-1670
SMILES	CC(C)(C)C(=O)NC1=CC2=C(C=C1)C3=CC=CC=C3C(=O)C2=O