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SGL5213 is a potent, oral active and low-absorbable sodium-dependent glucose cotransporter 1 (SGLT1) inhibitor, with IC50 values of 29 nM and 20 nM for hSGLT1 and hSGLT2, respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 14.93 mL | 74.64 mL | 149.29 mL |
| 0.5 mM | 2.99 mL | 14.93 mL | 29.86 mL |
| 1 mM | 1.49 mL | 7.46 mL | 14.93 mL |
| 5 mM | 0.3 mL | 1.49 mL | 2.99 mL |
*The above data is based on the productmolecular weight 669.85. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A18723 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 669.85 |
| Formula | C37H55N3O8 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1240305-17-2 |
| Synonyms | SGL 5213, SGL-5213 |
| SMILES | COC1=C([C@@H]2O[C@@H]([C@@H](O)[C@H](O)[C@H]2O)CO)C=C(CC3=CC=C(/C=C/C(C)(C)C(NC(C)(C)C(NCCN(C)C)=O)=O)C=C3)C(C(C)C)=C1 |
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