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SJB3-019A是有效的新型usp1抑制剂。SJB3-019A（IC50 = 0.0781 uM）在促进K562细胞中ID1降解和细胞毒性方面比SJB2-043强5倍。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 36.2 mL | 181 mL | 361.99 mL |
| 0.5 mM | 7.24 mL | 36.2 mL | 72.4 mL |
| 1 mM | 3.62 mL | 18.1 mL | 36.2 mL |
| 5 mM | 0.72 mL | 3.62 mL | 7.24 mL |
*The above data is based on the productmolecular weight 276.25. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A12822 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 276.25 |
| Formula | C16H8N2O3 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | N /A |
| SMILES | O=C(C1=C2OC(C3=CN=CC=C3)=N1)C4=CC=CC=C4C2=O |
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