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SMER3是体外和体内酵母SCF家族E3泛素连接酶（SCFMet30）的选择性抑制剂。诱导MET基因的表达；阻止细胞增殖。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 44.61 mL | 223.04 mL | 446.07 mL |
| 0.5 mM | 8.92 mL | 44.61 mL | 89.21 mL |
| 1 mM | 4.46 mL | 22.3 mL | 44.61 mL |
| 5 mM | 0.89 mL | 4.46 mL | 8.92 mL |
*The above data is based on the productmolecular weight 224.18. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A13253 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 224.18 |
| Formula | C11H4N4O2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 67200-34-4 |
| Synonyms | SMER 3, SMER3 |
| SMILES | C1=CC=C2C(=C1)C3=NC4=NON=C4N=C3C2=O |
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