产品详情

生物活性

STA-21是一种有前途的STAT-3抑制剂，可在类风湿关节炎的实验模型中相互调节Th17和Treg细胞，抑制小鼠和人类的破骨细胞生成并减轻自身免疫炎症。

靶点信息

STAT3

溶解度 *

In vitro	DMSO	21 mg/mL (68.55 mM)
	Water	Insoluble
	Ethanol	2 mg/mL (6.52 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	32.65 mL	163.23 mL	326.47 mL
0.5 mM	6.53 mL	32.65 mL	65.29 mL
1 mM	3.26 mL	16.32 mL	32.65 mL
5 mM	0.65 mL	3.26 mL	6.53 mL

*The above data is based on the productmolecular weight 306.31. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A15885
作用机制	Inhibitor (抑制剂)
M. Wt	306.31
Formula	C19H14O4
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	111540-00-2
Synonyms	Ochromycinone
SMILES	O=C1CC(C)CC2=CC=C3C(C(C4=CC=CC(O)=C4C3=O)=O)=C12