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STAT5抑制剂是一种细胞可渗透的非肽烟酰yl,可通过靶向其SH2结构域(针对STAT5βSH2结构域EPO肽结合活性的IC50 = 47μM)来抑制STAT5。
In vitro | DMSO | 20 mg/mL (68.19 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 34.09 mL | 170.47 mL | 340.95 mL |
0.5 mM | 6.82 mL | 34.09 mL | 68.19 mL |
1 mM | 3.41 mL | 17.05 mL | 34.09 mL |
5 mM | 0.68 mL | 3.41 mL | 6.82 mL |
*The above data is based on the productmolecular weight 293.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A13628 |
---|---|
作用机制 | Inhibitor (抑制剂) |
M. Wt | 293.3 |
Formula | C16H11N3O3 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 285986-31-4 |
Synonyms | Signal Transducers and Activators of Transcription 5 |
SMILES | C1=CC=C2C(=C1)C(=O)C(=CO2)C=NNC(=O)C3=CN=CC=C3 |
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