GSK-3
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GSK-3 inhibitor 1
Catalog No. A21803 -
VP3.15 dihydrobromide
Catalog No. A21789 PDE7/GSK3 inhibitorVP3.15 dihydrobromide is a potent, orally bioavailable and CNS-penetrant dual phosphodiesterase (PDE)7- glycogen synthase kinase (GSK)3 inhibitor, with IC50s of 1.59 μM and 0.88 μM for PDE7 and GSK-3, respectively. 了解更多 -
CHIR-99021 trihydrochloride
Catalog No. A21436 GSK-3α/β inhibitorCHIR-99021 trihydrochloride (CT99021 trihydrochloride) is a GSK-3α/β inhibitor with IC50 of 10 nM/6.7 nM. 了解更多 -
CHIR-99021 monohydrochloride
Catalog No. A21430 GSK-3α/β inhibitorCHIR-99021 monohydrochloride (CT99021 monohydrochloride) is a GSK-3α/β inhibitor with IC50 of 10 nM/6.7 nM; > 500-fold selectivity for GSK-3 versus its closest homologs CDC2 and ERK2, as well as other protein kinases. 了解更多 -
VP3.15
Catalog No. A18538 dual PDE7/GSK-3 inhibitorVP3.15 is a potent, orally bioavailable and CNS-penetrant dual phosphodiesterase (PDE)7- glycogen synthase kinase (GSK)3 inhibitor, with IC50s of 1.59 μM and 0.88 μM for PDE7 and GSK-3, respectively. VP3.15 has neuroprotective and neuroreparative activities, thus as potential combined anti-inflammatory and pro-remyelinating therapies for multiple sclerosis (MS). 了解更多 -
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最新产品
BIO
Catalog No. A17129 -
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Indirubin-3-monoxime
Catalog No. A16280 GSK-3β 抑制剂Indirubin-3'-monoxime是一种功能强大的GSK-3β抑制剂,IC50为22nM,也抑制CDK1/5(IC50 = 180/100 nM)。 了解更多 -
BIO-acetoxime
Catalog No. A15555 GSK-3 抑制剂BIO-acetoxime是一种有效的双重GSK3α/β抑制剂,IC50为10 nM,选择性比CDK5/p25,CDK2/cyclin A和 CDK1/cyclin B高240倍以上。 了解更多 -
Bikinin
Catalog No. A15526 -
IM-12
Catalog No. A14196 -
1-Azakenpaullone
Catalog No. A14303 GSK-3β 抑制剂1-Azakenpaullone是一种有效的选择性GSK-3β抑制剂,IC50为18 nM,选择性比CDK1/cyclin B和CDK5/p25高100倍。 了解更多 -
AR-A 014418
Catalog No. A13728 GSK-3 抑制剂AR-A 014418是一种选择性糖原合酶激酶3 (GSK-3) 抑制剂 (IC50 = 104 nM)。对GSK-3的特异性超过cdk2和cdk5(IC50值> 100μM)以及26种其他激酶。抑制β-淀粉样蛋白介导的海马片神经变性。 了解更多 -
AZD2858
Catalog No. A13060 -
Tideglusib
Catalog No. A11592 GSK-3 抑制剂Tideglusib是一种不可逆的,非ATP竞争性的GSK-3β抑制剂,无细胞试验中IC50为60 nM。用于治疗阿尔茨海默氏病和进行性核上性麻痹。 了解更多 -
TWS119
Catalog No. A11223 -
CHIR-98014
Catalog No. A11085 -
CHIR-99021
Catalog No. A10199 GSK-3 抑制剂CHIR99021是一种GSK-3α和GSK-3β抑制剂,IC50值分别为10和6.7 nM。 了解更多