SW033291

Name: SW033291
SKU: A15798

目录号: A15798

15-PGDH enzyme 抑制剂

SW033291 Chemical Structure

CAS NO. 459147-39-8

SW033291是15-PGDH的小分子抑制剂（Ki = 0.1 nM），可增加骨髓和其他组织中前列腺素PGE2的水平。

库存：现货

规格	价格	数量
5 mg	￥ 525.00
10 mg	￥ 840.00
25 mg	￥ 1,890.00

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生物活性

SW033291是15-PGDH的小分子抑制剂（Ki = 0.1 nM），可增加骨髓和其他组织中前列腺素PGE2的水平。

靶点信息

15-PGDH	15-PGDH
0.1 nM(Ki)	1.5 nM

溶解度 *

In vitro (25°C)	DMSO	77 mg/mL (186.62 mM)
	Water	Insoluble
	Ethanol	Warmed: 30 mg/mL (72.7 mM)
In vivo	5% DMSO+corn oil	9 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.24 mL	121.19 mL	242.37 mL
0.5 mM	4.85 mL	24.24 mL	48.47 mL
1 mM	2.42 mL	12.12 mL	24.24 mL
5 mM	0.48 mL	2.42 mL	4.85 mL

*The above data is based on the productmolecular weight 412.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A15798
作用机制	Inhibitor (抑制剂)
M. Wt	412.59
Formula	C21H20N2OS3
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	459147-39-8
Synonyms	SW 033291, SW-033291
SMILES	NC1=C(S(CCCC)=O)SC2=NC(C3=CC=CS3)=CC(C4=CC=CC=C4)=C21