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SW155246 is a potent and selective DNMT1 (DNA methyltransferase 1) inhibitor with IC50 of 1.2 μM. SW155246 induces re-expression of the tumor suppressor geneRASSF1 in A549 cells.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.4 mL | 132 mL | 263.99 mL |
| 0.5 mM | 5.28 mL | 26.4 mL | 52.8 mL |
| 1 mM | 2.64 mL | 13.2 mL | 26.4 mL |
| 5 mM | 0.53 mL | 2.64 mL | 5.28 mL |
*The above data is based on the productmolecular weight 378.8. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A22095 |
|---|---|
| M. Wt | 378.8 |
| Formula | C16H11ClN2O5S |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 2 years |
| CAS No. | 420092-79-1 |
| SMILES | ClC1=CC=C(S(NC2=CC=C(O)C3=C2C=CC=C3)(=O)=O)C=C1[N+]([O-])=O |
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