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SYN115是口服，有效和选择性的腺苷2a（A2a）受体抑制剂，作用于人类和恒河猴的 adenosine A2A 受体，Ki 值分别为 11.5 nM 和 6 nM。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.6 mL | 123 mL | 246 mL |
| 0.5 mM | 4.92 mL | 24.6 mL | 49.2 mL |
| 1 mM | 2.46 mL | 12.3 mL | 24.6 mL |
| 5 mM | 0.49 mL | 2.46 mL | 4.92 mL |
*The above data is based on the productmolecular weight 406.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A11560 |
|---|---|
| 作用机制 | Antagonist (拮抗剂) |
| M. Wt | 406.5 |
| Formula | C19H26N4O4S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 870070-55-6 |
| Synonyms | SYN115, Tozadenant |
| SMILES | CC1(CCN(CC1)C(=O)NC2=NC3=C(C=CC(=C3S2)N4CCOCC4)OC)O |
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