产品详情
Tafamidis meglumine (Fx-1006A) is a potent and selective transthyretin (TTR) stabilizer, shows comparable potency and efficacy to the mutumant homotetramers V30M-TTR, V122I-TTR and wild type WT-TTR, with EC50s of 2.7-3.2 μM.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 19.87 mL | 99.34 mL | 198.68 mL |
0.5 mM | 3.97 mL | 19.87 mL | 39.74 mL |
1 mM | 1.99 mL | 9.93 mL | 19.87 mL |
5 mM | 0.4 mL | 1.99 mL | 3.97 mL |
*The above data is based on the productmolecular weight 503.33. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A18045 |
---|---|
作用机制 | Stabilizer (稳定剂) |
M. Wt | 503.33 |
Formula | C21H24Cl2N2O8 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 951395-08-7 |
Synonyms | Fx-1006A, Fx1006A, Fx 1006A |
SMILES | O=C(C1=CC=C2N=C(C3=CC(Cl)=CC(Cl)=C3)OC2=C1)O.O[C@@H]([C@@H]([C@@H](CO)O)O)[C@@H](O)CNC |
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