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Dinaciclib (SCH 727965)

Catalog No. A11129
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CDK 抑制剂

Dinaciclib (SCH 727965)是一种有效且选择性的细胞周期蛋白依赖性激酶（CDK）抑制剂，选择性抑制CDK1，CDK2，CDK5和CDK9，IC50值分别为3、1、1和4 nM。了解更多

Product Citations (3)

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- Sepideh Izadi, .et al. Codelivery of HIF-1α siRNA and Dinaciclib by Carboxylated Graphene Oxide-Trimethyl Chitosan-Hyaluronate Nanoparticles Significantly Suppresses Cancer Cell Progression, Pharm Res, 2020, Sep 17;37(10):196 PMID: 32944844
- Shahin Hallaj, .et al. Inhibition of CD73 using folate targeted nanoparticles carrying anti-CD73 siRNA potentiates anticancer efficacy of Dinaciclib, Life Sci, 2020, Jul 26 PMID: 32726663
- Washio I, .et al. Impact of Breast Cancer Resistance Protein Expression on the In Vitro Efficacy of Anticancer Drugs in Pancreatic Cancer Cell Lines, Drug Metab Dispos, 2018, Mar;46(3):214-222 PMID: 29246888
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IC 261

Catalog No. A15764
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CK1δ and CK1ε 抑制剂

IC 261是CK1δ和CK1ε抑制剂。IC261对CK1的IC50为16 μM，对Cdk5的IC50为4.5 mM。了解更多

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