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使用 'CYP3A4' 作为标签的产品

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Clarithromycin

Catalog No. A10225
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cytochrome P4503A4 抑制剂

Clarithromycin是一种大环内酯类抗生素。它通过干扰细菌的蛋白质合成来防止细菌生长。了解更多

Product Citations (4)

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- Reiko Watanabe, .et al. Development of an In Silico Prediction Model for P-glycoprotein Efflux Potential in Brain Capillary Endothelial Cells toward the Prediction of Brain Penetration, J Med Chem, 2021, Mar 11;64(5):2725-2738 PMID: 33619967
- Takashi Azuma, .et al. Removal of pharmaceuticals in water by introduction of ozonated microbubbles, SEP PURIF TECHNOL, 2019, Apr; 212: 483-489
- Azuma T, .et al. Distribution of six anticancer drugs and a variety of other pharmaceuticals, and their sorption onto sediments, in an urban Japanese river, Environ Sci Pollut Res Int, 2017, Aug;24(23):19021-19030 PMID: 28660504
- Azuma T, .et al. Detection of pharmaceuticals and phytochemicals together with their metabolites in hospital effluents in Japan, and their contribution to sewage treatment plant influents, Sci Total Environ, 2016, Apr 1;548-549:189-197 PMID: 26802347
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Itraconazole (Sporanox)

Catalog No. A10489
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Itraconazole (Sporanox)是CYP3A4相对有效的抑制剂，IC50为6.1nM，用作三唑类抗真菌剂。了解更多

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- Paul Mark Medina, .et al. Revealing the anticancer potential of candidate drugs in vivo using Caenorhabditis elegans mutant strains, Transl Oncol, 2021, Jan;14(1):100940 PMID: 33221682
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PF 4981517

Catalog No. A12544
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CYP3A4 抑制剂

PF 4981517是一种有效且选择性的CYP3A4抑制剂（CYP3A4，CYP3A5和CYP3A7的IC50值分别为0.03、17和70 μM）。了解更多

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Piperine (1-Piperoylpiperidine)

Catalog No. A10734
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Piperine (1-Piperoylpiperidine)是生物碱，它与黑胡椒碱（胡椒碱的异构体）一起对黑胡椒和long胡椒具有刺激性。它也已用于某些形式的传统医学和作为杀虫剂。了解更多

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Ritonavir

Catalog No. A10799
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HIV Protease 抑制剂

Ritonavir是一种蛋白酶抑制剂，具有抗人类免疫缺陷病毒1型(hiv-1)的活性。蛋白酶抑制剂阻断hiv中被称为蛋白酶的部分，利托那韦抑制hiv病毒蛋白酶，这种蛋白酶防止gag-pol多蛋白的裂解，从而产生非感染性的未成熟病毒颗粒。了解更多

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Adooq Bioscience

使用 'CYP3A4' 作为标签的产品

Clarithromycin

Itraconazole (Sporanox)

PF 4981517

Piperine (1-Piperoylpiperidine)

Ritonavir

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