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使用 'HDAC2' 作为标签的产品

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BG45

Catalog No. A11361
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HDAC 抑制剂

BG45是一种HDAC I类抑制剂，对HDAC3具有选择性（IC50 = 289 nM）。它抑制HDAC1，HDAC2和HDAC6的效力大大降低（IC50分别为2、2和> 20μM）。了解更多

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BRD73954

Catalog No. A15489
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HDAC 抑制剂

BRD73954是一种小分子抑制剂，可有效抑制HDAC6和HDAC8（IC50分别为36和120 nM）。了解更多

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CI994 (Tacedinaline)

Catalog No. A11964
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HDAC 抑制剂

CI994 (Tacedinaline)是一种组蛋白脱乙酰基酶（HDAC）抑制剂，可在活细胞中诱导组蛋白超乙酰化。了解更多

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Domatinostat (4SC-202)

Catalog No. A14354
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HDAC 抑制剂

4SC-202是生物利用的苯甲酰胺和人I类组蛋白脱乙酰基酶（HDACs）同工酶1、2和3的抑制剂，具有潜在的抗肿瘤活性。了解更多

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Romidepsin (FK228 ,Depsipeptide)

Catalog No. A11920
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HDAC 抑制剂

Romidepsin (FK228,Depsipeptide)抑制HDAC1和HDAC2，IC50分别为1.6 nM和3.9 nM，但相对较弱地分别抑制HDAC4和HDAC6，IC50值为25 nM和79 nM。了解更多

Product Citations (7)

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- Yu-Fang Liu, .et al. Effects of dexmedetomidine on cognitive dysfunction andneuroinflammation via the HDAC2/HIF?\1α/PFKFB3 axis in amurine model of postoperative cognitive dysfunction, J Biochem Mol Toxicol, 2022, Jun;36(6):e23044 PMID: 35499365
- David Diaz-Carballo, .et al. Enhanced antitumoral activity of TLR7 agonists via activation of human endogenous retroviruses by HDAC inhibitors, Commun Biol, 2021, Mar 3;4(1):276 PMID: 33658617
- Eva Hesping, .et al. An ELISA method to assess HDAC inhibitor-induced alterations to P. falciparum histone lysine acetylation, Int J Parasitol Drugs Drug Resist, 2020, 14: 249-256
- Shariful Islam, .et al. Resistance to histone deacetylase inhibitors confers hypersensitivity to oncolytic reovirus therapy, Blood Adv, 2020, 4(20): 5297-5310 PMID: 33108458
- Elena Netchiporouk, .et al. Analysis of CTCL cell lines reveals important differences between mycosis fungoides/Sézary syndrome vs. HTLV-1+ leukemic cell lines, Oncotarget, 2017, Nov 10; 8(56): 95981-95998 PMID: 29221181
- Ivan V. Litvinov, .et al. Ectopic expression of cancer testis antigens in Cutaneous T-Cell Lymphoma (CTCL) patients, Clin Cancer Res, 2014, 20(14): 3799-3808 PMID: 24850846
- Ivan V Litvinov, .et al. Analysis of STAT4 expression in cutaneous T-cell lymphoma (CTCL) patients and patient-derived cell lines, Cell Cycle., 2014, 15; 13(18): 2975-2982 PMID: 25486484
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Santacruzamate A

Catalog No. A14236
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HDAC 抑制剂

Santacruzamate A (CAY10683)是一种有效的选择性HDAC抑制剂，对HDAC2的IC50为119 pM，选择性是其他HDAC的3600倍以上。了解更多

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Adooq Bioscience

使用 'HDAC2' 作为标签的产品

BG45

BRD73954

CI994 (Tacedinaline)

Domatinostat (4SC-202)

Romidepsin (FK228 ,Depsipeptide)

Santacruzamate A

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